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In silico simulation of a clinical trial with anti-CTLA-4 and anti-PD-L1 immunotherapies in metastatic breast cancer using a systems pharmacology model.
Wang, Hanwen; Milberg, Oleg; Bartelink, Imke H; Vicini, Paolo; Wang, Bing; Narwal, Rajesh; Roskos, Lorin; Santa-Maria, Cesar A; Popel, Aleksander S.
Afiliación
  • Wang H; Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Milberg O; Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Bartelink IH; Department of Medicine, University of California, San Francisco, CA, USA.
  • Vicini P; Clinical Pharmacology, Pharmacometrics and DMPK (CPD), MedImmune, South San Francisco, CA, USA.
  • Wang B; Department of Clinical Pharmacology and Pharmacy, Amsterdam UMC, Vrije Universiteit Amsterdam, The Netherlands.
  • Narwal R; Clinical Pharmacology, Pharmacometrics and DMPK, MedImmune, Cambridge, UK.
  • Roskos L; Amador Bioscience Inc, Pleasanton, CA 94588, USA.
  • Santa-Maria CA; Clinical Pharmacology and DMPK (CPD), MedImmune, Gaithersburg, MD, USA.
  • Popel AS; Clinical Pharmacology and DMPK (CPD), MedImmune, Gaithersburg, MD, USA.
R Soc Open Sci ; 6(5): 190366, 2019 May.
Article en En | MEDLINE | ID: mdl-31218069

Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: R Soc Open Sci Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: R Soc Open Sci Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos