Homoharringtonine stabilizes secondary structure of guanine-rich sequence existing in the 5'-untranslated region of Nrf2.

Kang, Jong-Su; Lee, June; Nam, Le Ba; Yoo, Ok-Kyung; Pham, Kim-Thanh; Duong, Thi-Hoai-Men; Keum, Young-Sam

Kang, Jong-Su; Lee, June; Nam, Le Ba; Yoo, Ok-Kyung; Pham, Kim-Thanh; Duong, Thi-Hoai-Men; Keum, Young-Sam.

Afiliación

Kang JS; College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University, 32 Dongguk-ro, Goyang, Gyeonggi-do 10326, South Korea.
Lee J; College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University, 32 Dongguk-ro, Goyang, Gyeonggi-do 10326, South Korea.
Nam LB; College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University, 32 Dongguk-ro, Goyang, Gyeonggi-do 10326, South Korea.
Yoo OK; College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University, 32 Dongguk-ro, Goyang, Gyeonggi-do 10326, South Korea.
Pham KT; College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University, 32 Dongguk-ro, Goyang, Gyeonggi-do 10326, South Korea.
Duong TH; College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University, 32 Dongguk-ro, Goyang, Gyeonggi-do 10326, South Korea.
Keum YS; College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University, 32 Dongguk-ro, Goyang, Gyeonggi-do 10326, South Korea. Electronic address: keum03@dongguk.edu.

Bioorg Med Chem Lett ; 29(16): 2189-2196, 2019 08 15.

Article en En | MEDLINE | ID: mdl-31270017

Asunto(s)

Regiones no Traducidas 5'/genética; Antineoplásicos Fitogénicos/uso terapéutico; Guanina/química; Homoharringtonina/uso terapéutico; Factor 2 Relacionado con NF-E2/genética; Antineoplásicos Fitogénicos/farmacología; Homoharringtonina/farmacología; Humanos

Palabras clave

5'-Untranslated region (5'-UTR); Antioxidant response element (ARE); Homoharringtonine (HHT); NF-E2-related factor 2 (NRF2)

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Regiones no Traducidas 5' / Factor 2 Relacionado con NF-E2 / Homoharringtonina / Guanina / Antineoplásicos Fitogénicos Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Corea del Sur

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google