Linkage Evidence for a Two-Locus Inheritance of LQT-Associated Seizures in a Multigenerational LQT Family With a Novel <i>KCNQ1</i> Loss-of-Function Mutation.

Prüss, Harald; Gessner, Guido; Heinemann, Stefan H; Rüschendorf, Franz; Ruppert, Ann-Kathrin; Schulz, Herbert; Sander, Thomas; Rimpau, Wilhelm

Linkage Evidence for a Two-Locus Inheritance of LQT-Associated Seizures in a Multigenerational LQT Family With a Novel KCNQ1 Loss-of-Function Mutation.

Prüss, Harald; Gessner, Guido; Heinemann, Stefan H; Rüschendorf, Franz; Ruppert, Ann-Kathrin; Schulz, Herbert; Sander, Thomas; Rimpau, Wilhelm.

Afiliación

Prüss H; Department of Neurology and Experimental Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Gessner G; German Center for Neurodegenerative Diseases (DZNE) Berlin, Bonn, Germany.
Heinemann SH; Department of Biophysics, Center for Molecular Biomedicine, Friedrich Schiller University Jena & Jena University Hospital, Jena, Germany.
Rüschendorf F; Department of Biophysics, Center for Molecular Biomedicine, Friedrich Schiller University Jena & Jena University Hospital, Jena, Germany.
Ruppert AK; Max Delbrück Centre for Molecular Medicine, Berlin, Germany.
Schulz H; Cologne Center for Genomics, University of Cologne, Cologne, Germany.
Sander T; Cologne Center for Genomics, University of Cologne, Cologne, Germany.
Rimpau W; Cologne Center for Genomics, University of Cologne, Cologne, Germany.

Front Neurol ; 10: 648, 2019.

Article en En | MEDLINE | ID: mdl-31293497

Palabras clave

KCNQ1; LQT syndrome; familial epilepsy; genetic modifier; risk haplotype

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Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: Front Neurol Año: 2019 Tipo del documento: Article País de afiliación: Alemania

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