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Functional divergence caused by mutations in an energetic hotspot in ERK2.
Taylor, Clinton A; Cormier, Kevin W; Keenan, Shannon E; Earnest, Svetlana; Stippec, Steve; Wichaidit, Chonlarat; Juang, Yu-Chi; Wang, Junmei; Shvartsman, Stanislav Y; Goldsmith, Elizabeth J; Cobb, Melanie H.
Afiliación
  • Taylor CA; Department of Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390.
  • Cormier KW; Department of Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390.
  • Keenan SE; Department of Chemical and Biological Engineering, Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544.
  • Earnest S; Department of Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390.
  • Stippec S; Department of Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390.
  • Wichaidit C; Department of Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390.
  • Juang YC; Department of Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390.
  • Wang J; Department of Biophysics, UT Southwestern Medical Center, Dallas, TX 75390.
  • Shvartsman SY; Department of Chemical and Biological Engineering, Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544.
  • Goldsmith EJ; Department of Biophysics, UT Southwestern Medical Center, Dallas, TX 75390.
  • Cobb MH; Department of Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390; melanie.cobb@utsouthwestern.edu.
Proc Natl Acad Sci U S A ; 116(31): 15514-15523, 2019 07 30.
Article en En | MEDLINE | ID: mdl-31296562
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas de Drosophila / Quinasas MAP Reguladas por Señal Extracelular / Drosophila melanogaster / Mutación Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas de Drosophila / Quinasas MAP Reguladas por Señal Extracelular / Drosophila melanogaster / Mutación Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2019 Tipo del documento: Article