Novel Therapies for Biofilm-Based Candida spp. Infections.
Adv Exp Med Biol
; 1214: 93-123, 2019.
Article
en En
| MEDLINE
| ID: mdl-31321751
ABSTRACT
The presence of fungal infections continue to grow worldwide, mostly in immunosuppressed patients, and in individuals with continued antimicrobial treatments. Candida spp. are the most common yeasts involved in these disorders, being associated with a high rate of antifungal resistance and an increased ability to form biofilms, which make the treatment of these infections difficult. This review aims to present and discuss the main biofilm-related infections cause by several Candida spp. and novel therapies that are currently available in the clinical, scientific and academic environment. New drugs with promising antifungal activity, natural approaches (e.g. probiotics, essential oils, plant extracts, honey) and a final consideration on alternative methodologies, such as photodynamic therapy are presented and discussed.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Candidiasis
/
Biopelículas
Límite:
Humans
Idioma:
En
Revista:
Adv Exp Med Biol
Año:
2019
Tipo del documento:
Article
País de afiliación:
Eslovaquia