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Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV.
Niu, Qingli; Liu, Zhiqing; Alamer, Edrous; Fan, Xiuzhen; Chen, Haiying; Endsley, Janice; Gelman, Benjamin B; Tian, Bing; Kim, Jerome H; Michael, Nelson L; Robb, Merlin L; Ananworanich, Jintanat; Zhou, Jia; Hu, Haitao.
Afiliación
  • Niu Q; Department of Microbiology and Immunology, University of Texas Medical Branch (UTMB), Galveston, Texas, USA.
  • Liu Z; Institute for Human Infections and Immunity, Sealy Institute for Vaccine Sciences.
  • Alamer E; Chemical Biology Program, Department of Pharmacology and Toxicology.
  • Fan X; Department of Microbiology and Immunology, University of Texas Medical Branch (UTMB), Galveston, Texas, USA.
  • Chen H; Institute for Human Infections and Immunity, Sealy Institute for Vaccine Sciences.
  • Endsley J; Department of Microbiology and Immunology, University of Texas Medical Branch (UTMB), Galveston, Texas, USA.
  • Gelman BB; Institute for Human Infections and Immunity, Sealy Institute for Vaccine Sciences.
  • Tian B; Chemical Biology Program, Department of Pharmacology and Toxicology.
  • Kim JH; Department of Microbiology and Immunology, University of Texas Medical Branch (UTMB), Galveston, Texas, USA.
  • Michael NL; Institute for Human Infections and Immunity, Sealy Institute for Vaccine Sciences.
  • Robb ML; Department of Pathology, and.
  • Ananworanich J; Department of Internal Medicine, Sealy Center for Molecular Medicine, UTMB, Galveston, Texas, USA.
  • Zhou J; International Vaccine Institute, Gwanak-gu, Seoul, South Korea.
  • Hu H; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
J Clin Invest ; 129(8): 3361-3373, 2019 07 22.
Article en En | MEDLINE | ID: mdl-31329163
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Factores de Transcripción / Infecciones por VIH / VIH-1 / Proteínas de Ciclo Celular / Antirretrovirales Tipo de estudio: Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: J Clin Invest Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Factores de Transcripción / Infecciones por VIH / VIH-1 / Proteínas de Ciclo Celular / Antirretrovirales Tipo de estudio: Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: J Clin Invest Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos