Binding and photodynamic action of the cationic zinc phthalocyanines with different types of DNA toward understanding of their cancer therapy activity.

McRae, Ewan K S; Nevonen, Dustin E; McKenna, Sean A; Nemykin, Victor N

McRae, Ewan K S; Nevonen, Dustin E; McKenna, Sean A; Nemykin, Victor N.

Afiliación

McRae EKS; Department of Chemistry, University of Manitoba, 144 Dysart Rd, R3T 2N2 Winnipeg, MB, Canada.
Nevonen DE; Department of Chemistry, University of Manitoba, 144 Dysart Rd, R3T 2N2 Winnipeg, MB, Canada.
McKenna SA; Department of Chemistry, University of Manitoba, 144 Dysart Rd, R3T 2N2 Winnipeg, MB, Canada. Electronic address: Sean.McKenna@umanitoba.ca.
Nemykin VN; Department of Chemistry, University of Manitoba, 144 Dysart Rd, R3T 2N2 Winnipeg, MB, Canada. Electronic address: Victor.Nemykin@umanitoba.ca.

J Inorg Biochem ; 199: 110793, 2019 10.

Article en En | MEDLINE | ID: mdl-31357069

Asunto(s)

ADN/química; Indoles/química; Compuestos Organometálicos/química; Comunicación Celular; Dicroismo Circular; Citoplasma/metabolismo; Humanos; Isoindoles; Células MCF-7; Microscopía Confocal; Neoplasias/terapia; Fotoquimioterapia; Fármacos Fotosensibilizantes/química; Oxígeno Singlete/química; Compuestos de Zinc

Palabras clave

Confocal microscopy; DNA binding; Photodynamic therapy; Phthalocyanine; Singlet oxygen generation

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Compuestos Organometálicos / ADN / Indoles Límite: Humans Idioma: En Revista: J Inorg Biochem Año: 2019 Tipo del documento: Article País de afiliación: Canadá

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