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Inhaled corticosteroid suppression of cathelicidin drives dysbiosis and bacterial infection in chronic obstructive pulmonary disease.
Singanayagam, Aran; Glanville, Nicholas; Cuthbertson, Leah; Bartlett, Nathan W; Finney, Lydia J; Turek, Elena; Bakhsoliani, Eteri; Calderazzo, Maria Adelaide; Trujillo-Torralbo, Maria-Belen; Footitt, Joseph; James, Phillip L; Fenwick, Peter; Kemp, Samuel V; Clarke, Thomas B; Wedzicha, Jadwiga A; Edwards, Michael R; Moffatt, Miriam; Cookson, William O; Mallia, Patrick; Johnston, Sebastian L.
Afiliación
  • Singanayagam A; National Heart and Lung Institute, St Mary's Campus, Imperial College London, London W2 1PG, UK. a.singanayagam@imperial.ac.uk s.johnston@imperial.ac.uk.
  • Glanville N; National Heart and Lung Institute, St Mary's Campus, Imperial College London, London W2 1PG, UK.
  • Cuthbertson L; National Heart and Lung Institute, Brompton Campus, Imperial College London, London SW3 6LY, UK.
  • Bartlett NW; National Heart and Lung Institute, St Mary's Campus, Imperial College London, London W2 1PG, UK.
  • Finney LJ; Faculty of Health and Medicine and Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and University of Newcastle, Newcastle, NSW 2305, Australia.
  • Turek E; National Heart and Lung Institute, Brompton Campus, Imperial College London, London SW3 6LY, UK.
  • Bakhsoliani E; National Heart and Lung Institute, Brompton Campus, Imperial College London, London SW3 6LY, UK.
  • Calderazzo MA; National Heart and Lung Institute, St Mary's Campus, Imperial College London, London W2 1PG, UK.
  • Trujillo-Torralbo MB; National Heart and Lung Institute, St Mary's Campus, Imperial College London, London W2 1PG, UK.
  • Footitt J; National Heart and Lung Institute, St Mary's Campus, Imperial College London, London W2 1PG, UK.
  • James PL; National Heart and Lung Institute, St Mary's Campus, Imperial College London, London W2 1PG, UK.
  • Fenwick P; National Heart and Lung Institute, Brompton Campus, Imperial College London, London SW3 6LY, UK.
  • Kemp SV; National Heart and Lung Institute, Brompton Campus, Imperial College London, London SW3 6LY, UK.
  • Clarke TB; Royal Brompton Hospital, Fulham Road, London SW2 6NP, UK.
  • Wedzicha JA; MRC Centre for Molecular Bacteriology and Infection, Department of Medicine, Imperial College London, London SW7 2AZ, UK.
  • Edwards MR; National Heart and Lung Institute, Brompton Campus, Imperial College London, London SW3 6LY, UK.
  • Moffatt M; National Heart and Lung Institute, St Mary's Campus, Imperial College London, London W2 1PG, UK.
  • Cookson WO; National Heart and Lung Institute, Brompton Campus, Imperial College London, London SW3 6LY, UK.
  • Mallia P; National Heart and Lung Institute, Brompton Campus, Imperial College London, London SW3 6LY, UK.
  • Johnston SL; National Heart and Lung Institute, St Mary's Campus, Imperial College London, London W2 1PG, UK.
Sci Transl Med ; 11(507)2019 08 28.
Article en En | MEDLINE | ID: mdl-31462509
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Corticoesteroides / Péptidos Catiónicos Antimicrobianos / Enfermedad Pulmonar Obstructiva Crónica / Disbiosis Límite: Aged / Animals / Female / Humans / Male Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2019 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Corticoesteroides / Péptidos Catiónicos Antimicrobianos / Enfermedad Pulmonar Obstructiva Crónica / Disbiosis Límite: Aged / Animals / Female / Humans / Male Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2019 Tipo del documento: Article