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[Epidemiological, pathological and prognostic characteristics of bladder cancer in elderly patients]. / Spécificités épidémiologiques, pathologiques et pronostiques du cancer de la vessie chez les patients âgés.
Neuzillet, Y; Geiss, R; Caillet, P; Paillaud, E; Mongiat-Artus, P.
Afiliación
  • Neuzillet Y; Service d'urologie et de transplantation rénale, hôpital Foch, université de Versailles - Saint-Quentin-en-Yvelines, 40, rue Worth, 92150 Suresnes, France. Electronic address: y.neuzillet@hopital-foch.org.
  • Geiss R; Unité d'oncogériatrie, service de gériatrie, hôpital européen Georges-Pompidou, université de Paris Descartes, 20, rue Leblanc, 75908 Paris cedex 15, France.
  • Caillet P; Unité d'oncogériatrie, service de gériatrie, hôpital européen Georges-Pompidou, université de Paris Descartes, 20, rue Leblanc, 75908 Paris cedex 15, France.
  • Paillaud E; Unité d'oncogériatrie, service de gériatrie, hôpital européen Georges-Pompidou, université de Paris Descartes, 20, rue Leblanc, 75908 Paris cedex 15, France.
  • Mongiat-Artus P; Unité de chirurgie et d'anesthésie ambulatoires, service d'urologie, Inserm UMR, S1165, hôpital Saint-Louis, université de Paris-7-Denis-Diderot, 1, avenue Claude-Vellefaux, 75010 Paris, France.
Prog Urol ; 29(14): 840-848, 2019 Nov.
Article en Fr | MEDLINE | ID: mdl-31471266
AIM: To define and present explanations for the epidemiological, pathological and prognostic differences in bladder cancer in elderly patients. METHOD: Bibliographical search was performed from the Medline bibliographic database (NLM Pubmed tool) and Embase focused on: bladder cancer, carcinogenesis, elderly, epidemiology, prognosis. RESULTS: Bladder cancer is a growing concern for the elderly first and foremost and with an impact, mainly those who are consumers or former users of tobacco, whose therefore frequently have comorbidities associated with this consumption. The initiated carcinogenesis extends with the life length of patients, increasing the prevalence of bladder cancer. Aging promotes carcinogenesis by both potentiating its genetic abnormalities and reducing the immune system performance of the aged host to destroy cancer cells. The delay in the diagnosis of bladder cancer in elderly patients is explained and make up for the time could improve the prognosis. CONCLUSION: Regardless of variations in therapeutic effect and morbidity and mortality of treatments, aging promotes the occurrence and aggressiveness of bladder cancer. The incentive to stop exposure to carcinogens and the search for bladder cancer in patients with hematuria should not reduce with advanced age but instead be promoted in order to improve the prognosis.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias de la Vejiga Urinaria Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Aged / Humans Idioma: Fr Revista: Prog Urol Asunto de la revista: UROLOGIA Año: 2019 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias de la Vejiga Urinaria Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Aged / Humans Idioma: Fr Revista: Prog Urol Asunto de la revista: UROLOGIA Año: 2019 Tipo del documento: Article