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Afatinib versus methotrexate as second-line treatment in Asian patients with recurrent or metastatic squamous cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 3): an open-label, randomised phase III trial.
Guo, Y; Ahn, M-J; Chan, A; Wang, C-H; Kang, J-H; Kim, S-B; Bello, M; Arora, R S; Zhang, Q; He, X; Li, P; Dechaphunkul, A; Kumar, V; Kamble, K; Li, W; Kandil, A; Cohen, E E W; Geng, Y; Zografos, E; Tang, P Z.
Afiliación
  • Guo Y; Department of Medical Oncology, Shanghai East Hospital, Tongji University, Shanghai, China. Electronic address: pattrickguo@gmail.com.
  • Ahn MJ; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  • Chan A; State Key Laboratory in Translational Oncology, The Chinese University of Hong Kong, Hong Kong, China.
  • Wang CH; Department of Medical Oncology, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan.
  • Kang JH; The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul.
  • Kim SB; Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
  • Bello M; Department of Oncology, St Luke's Medical Center, Quezon City, Philippines.
  • Arora RS; Department Oncology, Sujan Surgical Cancer Hospital and Amravati Cancer Foundation, Amravati, India.
  • Zhang Q; Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China.
  • He X; Department of Medical Oncology, Cancer Hospital, Chinese Academy of Medical Science, Beijing.
  • Li P; West China Hospital, Sichuan University, Chengdu, China.
  • Dechaphunkul A; Division of Medical Oncology, Prince of Songkla University, Songkhla, Thailand.
  • Kumar V; Department of Surgical Oncology, King George's Medical University, Lucknow.
  • Kamble K; Department of Medicine, Government Medical College and Hospital, Nagpur, India.
  • Li W; Department of Hematology and Oncology, First Hospital Affiliated to Jilin University, Jilin, China.
  • Kandil A; Internal Medicine, Alexandria University Hospital, Alexandria, Egypt.
  • Cohen EEW; Department of Medicine, University of California, San Diego, USA.
  • Geng Y; Biostatistics, Boehringer Ingelheim (China) Investment Co., Ltd, China.
  • Zografos E; Clinical Development and Medical Affairs, Boehringer Ingelheim Ltd, Bracknell, Berkshire, UK.
  • Tang PZ; Department of Oncology, Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Ann Oncol ; 30(11): 1831-1839, 2019 11 01.
Article en En | MEDLINE | ID: mdl-31501887

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Metotrexato / Carcinoma de Células Escamosas de Cabeza y Cuello / Afatinib / Neoplasias de Cabeza y Cuello / Recurrencia Local de Neoplasia / Antineoplásicos Tipo de estudio: Clinical_trials Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Oncol Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Metotrexato / Carcinoma de Células Escamosas de Cabeza y Cuello / Afatinib / Neoplasias de Cabeza y Cuello / Recurrencia Local de Neoplasia / Antineoplásicos Tipo de estudio: Clinical_trials Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Oncol Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article