Direct comparison of target-reactivity and cross-reactivity induced by CAR- and BiTE-redirected T cells for the development of antibody-based T-cell therapy.

Maruta, Masaki; Ochi, Toshiki; Tanimoto, Kazushi; Asai, Hiroaki; Saitou, Takashi; Fujiwara, Hiroshi; Imamura, Takeshi; Takenaka, Katsuto; Yasukawa, Masaki

Maruta, Masaki; Ochi, Toshiki; Tanimoto, Kazushi; Asai, Hiroaki; Saitou, Takashi; Fujiwara, Hiroshi; Imamura, Takeshi; Takenaka, Katsuto; Yasukawa, Masaki.

Afiliación

Maruta M; Department of Hematology, Clinical Immunology, and Infectious Diseases, Ehime University Graduate School of Medicine, 791-0295, Toon, Ehime, Japan.
Ochi T; Department of Hematology, Clinical Immunology, and Infectious Diseases, Ehime University Graduate School of Medicine, 791-0295, Toon, Ehime, Japan. ochi.toshiki.eg@ehime-u.ac.jp.
Tanimoto K; Division of Immune Regulation, Proteo-Science Center, Ehime University, 791-0295, Toon, Ehime, Japan. ochi.toshiki.eg@ehime-u.ac.jp.
Asai H; Department of Hematology, Clinical Immunology, and Infectious Diseases, Ehime University Graduate School of Medicine, 791-0295, Toon, Ehime, Japan.
Saitou T; Department of Hematology, Clinical Immunology, and Infectious Diseases, Ehime University Graduate School of Medicine, 791-0295, Toon, Ehime, Japan.
Fujiwara H; Department of Molecular Medicine for Pathogenesis, Ehime University Graduate School of Medicine, 791-0295, Toon, Ehime, Japan.
Imamura T; Department of Hematology, Clinical Immunology, and Infectious Diseases, Ehime University Graduate School of Medicine, 791-0295, Toon, Ehime, Japan.
Takenaka K; Department of Molecular Medicine for Pathogenesis, Ehime University Graduate School of Medicine, 791-0295, Toon, Ehime, Japan.
Yasukawa M; Department of Hematology, Clinical Immunology, and Infectious Diseases, Ehime University Graduate School of Medicine, 791-0295, Toon, Ehime, Japan.

Sci Rep ; 9(1): 13293, 2019 09 16.

Article en En | MEDLINE | ID: mdl-31527633

Asunto(s)

Antígenos de Neoplasias/inmunología; Antígeno HLA-A2/inmunología; Inmunoterapia Adoptiva/métodos; Proteínas de la Membrana/inmunología; Mieloma Múltiple/terapia; Receptores Quiméricos de Antígenos/inmunología; Linfocitos T Citotóxicos/trasplante; Línea Celular Tumoral; Humanos; Región Variable de Inmunoglobulina/inmunología; Activación de Linfocitos/inmunología; Mieloma Múltiple/inmunología; Linfocitos T Citotóxicos/inmunología

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Linfocitos T Citotóxicos / Antígeno HLA-A2 / Inmunoterapia Adoptiva / Receptores Quiméricos de Antígenos / Proteínas de la Membrana / Mieloma Múltiple / Antígenos de Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Sci Rep Año: 2019 Tipo del documento: Article País de afiliación: Japón

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