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Fine-tuning the properties of the thrombin binding aptamer through cyclization: Effect of the 5'-3' connecting linker on the aptamer stability and anticoagulant activity.
Riccardi, Claudia; Meyer, Albert; Vasseur, Jean-Jacques; Russo Krauss, Irene; Paduano, Luigi; Morvan, François; Montesarchio, Daniela.
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  • Riccardi C; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 21, I-80126 Napoli, Italy.
  • Meyer A; Institut des Biomolécules Max Mousseron, Université de Montpellier, CNRS, ENSCM, Montpellier, France.
  • Vasseur JJ; Institut des Biomolécules Max Mousseron, Université de Montpellier, CNRS, ENSCM, Montpellier, France.
  • Russo Krauss I; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 21, I-80126 Napoli, Italy; CSGI - Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase, Via della Lastruccia 3, I-50019 Sesto Fiorentino (Fi), Italy.
  • Paduano L; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 21, I-80126 Napoli, Italy; CSGI - Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase, Via della Lastruccia 3, I-50019 Sesto Fiorentino (Fi), Italy.
  • Morvan F; Institut des Biomolécules Max Mousseron, Université de Montpellier, CNRS, ENSCM, Montpellier, France. Electronic address: francois.morvan@umontpellier.fr.
  • Montesarchio D; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 21, I-80126 Napoli, Italy. Electronic address: daniela.montesarchio@unina.it.
Bioorg Chem ; 94: 103379, 2020 01.
Article en En | MEDLINE | ID: mdl-31699393
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Coagulación Sanguínea / Aptámeros de Nucleótidos / Anticoagulantes Idioma: En Revista: Bioorg Chem Año: 2020 Tipo del documento: Article País de afiliación: Italia
Texto completo
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XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Coagulación Sanguínea / Aptámeros de Nucleótidos / Anticoagulantes Idioma: En Revista: Bioorg Chem Año: 2020 Tipo del documento: Article País de afiliación: Italia