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A High-Throughput BRET Cellular Target Engagement Assay Links Biochemical to Cellular Activity for Bruton's Tyrosine Kinase.
Ong, L L; Vasta, J D; Monereau, L; Locke, G; Ribeiro, H; Pattoli, M A; Skala, S; Burke, J R; Watterson, S H; Tino, J A; Meisenheimer, P L; Arey, B; Lippy, J; Zhang, L; Robers, M B; Tebben, A; Chaudhry, C.
Afiliación
  • Ong LL; Leads Discovery and Optimization, Bristol Myers Squibb, Princeton, NJ, USA.
  • Vasta JD; Promega Corporation, Madison, WI, USA.
  • Monereau L; Leads Discovery and Optimization, Bristol Myers Squibb, Princeton, NJ, USA.
  • Locke G; Leads Discovery and Optimization, Bristol Myers Squibb, Princeton, NJ, USA.
  • Ribeiro H; Leads Discovery and Optimization, Bristol Myers Squibb, Princeton, NJ, USA.
  • Pattoli MA; Immunoscience Discovery Biology, Bristol Myers Squibb, Princeton, NJ, USA.
  • Skala S; Immunoscience Discovery Biology, Bristol Myers Squibb, Princeton, NJ, USA.
  • Burke JR; Immunoscience Discovery Biology, Bristol Myers Squibb, Princeton, NJ, USA.
  • Watterson SH; Immunosciences Discovery Chemistry, Bristol Myers Squibb, Princeton, NJ, USA.
  • Tino JA; Immunosciences Discovery Chemistry, Bristol Myers Squibb, Princeton, NJ, USA.
  • Meisenheimer PL; Promega Corporation, Madison, WI, USA.
  • Arey B; Leads Discovery and Optimization, Bristol Myers Squibb, Princeton, NJ, USA.
  • Lippy J; Leads Discovery and Optimization, Bristol Myers Squibb, Princeton, NJ, USA.
  • Zhang L; Leads Discovery and Optimization, Bristol Myers Squibb, Princeton, NJ, USA.
  • Robers MB; Promega Corporation, Madison, WI, USA.
  • Tebben A; Molecular Structure and Design, Molecular Discovery Technologies, Bristol Myers Squibb, Princeton, NJ, USA.
  • Chaudhry C; Leads Discovery and Optimization, Bristol Myers Squibb, Princeton, NJ, USA.
SLAS Discov ; 25(2): 176-185, 2020 Feb.
Article en En | MEDLINE | ID: mdl-31709883
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Transferencia Resonante de Energía de Fluorescencia / Inhibidores de Proteínas Quinasas / Ensayos Analíticos de Alto Rendimiento / Agammaglobulinemia Tirosina Quinasa Límite: Humans Idioma: En Revista: SLAS Discov Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Transferencia Resonante de Energía de Fluorescencia / Inhibidores de Proteínas Quinasas / Ensayos Analíticos de Alto Rendimiento / Agammaglobulinemia Tirosina Quinasa Límite: Humans Idioma: En Revista: SLAS Discov Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos