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Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances.
Dreser, Nadine; Madjar, Katrin; Holzer, Anna-Katharina; Kapitza, Marion; Scholz, Christopher; Kranaster, Petra; Gutbier, Simon; Klima, Stefanie; Kolb, David; Dietz, Christian; Trefzer, Timo; Meisig, Johannes; van Thriel, Christoph; Henry, Margit; Berthold, Michael R; Blüthgen, Nils; Sachinidis, Agapios; Rahnenführer, Jörg; Hengstler, Jan G; Waldmann, Tanja; Leist, Marcel.
Afiliación
  • Dreser N; In Vitro Toxicology and Biomedicine, Department Inaugurated By the Doerenkamp-Zbinden Chair Foundation, University of Konstanz, Box 657, 78457, Konstanz, Germany.
  • Madjar K; Department of Statistics, TU Dortmund, 44221, Dortmund, Germany.
  • Holzer AK; In Vitro Toxicology and Biomedicine, Department Inaugurated By the Doerenkamp-Zbinden Chair Foundation, University of Konstanz, Box 657, 78457, Konstanz, Germany.
  • Kapitza M; In Vitro Toxicology and Biomedicine, Department Inaugurated By the Doerenkamp-Zbinden Chair Foundation, University of Konstanz, Box 657, 78457, Konstanz, Germany.
  • Scholz C; In Vitro Toxicology and Biomedicine, Department Inaugurated By the Doerenkamp-Zbinden Chair Foundation, University of Konstanz, Box 657, 78457, Konstanz, Germany.
  • Kranaster P; In Vitro Toxicology and Biomedicine, Department Inaugurated By the Doerenkamp-Zbinden Chair Foundation, University of Konstanz, Box 657, 78457, Konstanz, Germany.
  • Gutbier S; Konstanz Research School Chemical Biology (KoRS-CB), University of Konstanz, 78457, Konstanz, Germany.
  • Klima S; In Vitro Toxicology and Biomedicine, Department Inaugurated By the Doerenkamp-Zbinden Chair Foundation, University of Konstanz, Box 657, 78457, Konstanz, Germany.
  • Kolb D; Roche Pharma Development, Grenzacherstrasse, 4070, Basel, Switzerland.
  • Dietz C; In Vitro Toxicology and Biomedicine, Department Inaugurated By the Doerenkamp-Zbinden Chair Foundation, University of Konstanz, Box 657, 78457, Konstanz, Germany.
  • Trefzer T; Department of Computer and Information Science, University of Konstanz, 78457, Konstanz, Germany.
  • Meisig J; KNIME GmbH, 78467, Konstanz, Germany.
  • van Thriel C; Department of Computer and Information Science, University of Konstanz, 78457, Konstanz, Germany.
  • Henry M; KNIME GmbH, 78467, Konstanz, Germany.
  • Berthold MR; In Vitro Toxicology and Biomedicine, Department Inaugurated By the Doerenkamp-Zbinden Chair Foundation, University of Konstanz, Box 657, 78457, Konstanz, Germany.
  • Blüthgen N; Digital Health Center, Berlin Institute of Health (BIH), Charité-Universitätsmedizin, 10117, Berlin, Germany.
  • Sachinidis A; Institute of Pathology, Charité-Universitätsmedizin, 10117, Berlin, Germany.
  • Rahnenführer J; Leibniz Research Centre for Working Environment and Human Factors (IfADo), Technical University of Dortmund, 44139, Dortmund, Germany.
  • Hengstler JG; Center of Physiology and Pathophysiology, Institute of Neurophysiology, University of Cologne (UKK), 50931, Cologne, Germany.
  • Waldmann T; Department of Computer and Information Science, University of Konstanz, 78457, Konstanz, Germany.
  • Leist M; Institute of Pathology, Charité-Universitätsmedizin, 10117, Berlin, Germany.
Arch Toxicol ; 94(1): 151-171, 2020 01.
Article en En | MEDLINE | ID: mdl-31712839
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Formación de Roseta / Pruebas de Toxicidad / Células-Madre Neurales / Trastornos del Neurodesarrollo / Neurotoxinas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Arch Toxicol Año: 2020 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Formación de Roseta / Pruebas de Toxicidad / Células-Madre Neurales / Trastornos del Neurodesarrollo / Neurotoxinas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Arch Toxicol Año: 2020 Tipo del documento: Article País de afiliación: Alemania