Management of Cow's Milk Allergy from an Immunological Perspective: What Are the Options?
Nutrients
; 11(11)2019 11 11.
Article
en En
| MEDLINE
| ID: mdl-31718010
The immunological mechanism underlying Immunoglobuline E (IgE)-mediated cow's milk allergy has been subject to investigations for many years. Identification of the key immune cells (mast cells, B cells) and molecules (IgE) in the allergic process has led to the understanding that avoidance of IgE-crosslinking epitopes is effective in the reduction of allergic symptoms but it cannot be envisioned as a treatment. For the treatment and prevention of IgE-mediated cow's milk allergy, it is thought that the induction of a sustained state of immunological tolerance is needed. In this review, we will discuss various approaches aimed at achieving immunological tolerance and their success. Furthermore, we will speculate on the involved immunological mechanism.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Hipersensibilidad a la Leche
Límite:
Adult
/
Animals
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Child
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Humans
/
Infant
Idioma:
En
Revista:
Nutrients
Año:
2019
Tipo del documento:
Article
País de afiliación:
Países Bajos