Single-Cell Transcriptomics: A High-Resolution Avenue for Plant Functional Genomics.
Trends Plant Sci
; 25(2): 186-197, 2020 02.
Article
en En
| MEDLINE
| ID: mdl-31780334
ABSTRACT
Plant function is the result of the concerted action of single cells in different tissues. Advances in RNA-seq technologies and tissue processing allow us now to capture transcriptional changes at single-cell resolution. The incredible potential of single-cell RNA-seq lies in the novel ability to study and exploit regulatory processes in complex tissues based on the behaviour of single cells. Importantly, the independence from reporter lines allows the analysis of any given tissue in any plant. While there are challenges associated with the handling and analysis of complex datasets, the opportunities are unique to generate knowledge of tissue functions in unprecedented detail and to facilitate the application of such information by mapping cellular functions and interactions in a plant cell atlas.
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Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Genómica
/
Transcriptoma
Idioma:
En
Revista:
Trends Plant Sci
Asunto de la revista:
BOTANICA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Reino Unido