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Selenium bioisosteric replacement of adenosine derivatives promoting adiponectin secretion increases the binding affinity to peroxisome proliferator-activated receptor δ.
An, Seungchan; Yu, Jinha; Choi, Hongseok; Ko, Hyejin; Ahn, Sungjin; Shin, Jeayoung C; Pyo, Jeong Joo; Jeong, Lak Shin; Noh, Minsoo.
Afiliación
  • An S; College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea; Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
  • Yu J; College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea; Pharmaceutical Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
  • Choi H; College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea; Pharmaceutical Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
  • Ko H; College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea; Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
  • Ahn S; College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea; Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
  • Shin JC; College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea; Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
  • Pyo JJ; College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea; Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
  • Jeong LS; College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea; Pharmaceutical Research Institute, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: lakjeong@snu.ac.kr.
  • Noh M; College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea; Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: minsoonoh@snu.ac.kr.
Bioorg Med Chem ; 28(1): 115226, 2020 01 01.
Article en En | MEDLINE | ID: mdl-31806266
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Selenio / Adenosina / PPAR delta / Adiponectina Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Selenio / Adenosina / PPAR delta / Adiponectina Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article