Passive exposure of non-smokers to E-Cigarette aerosols: Sensory irritation, timing and association with volatile organic compounds.
Environ Res
; 182: 108963, 2020 03.
Article
en En
| MEDLINE
| ID: mdl-31837549
ABSTRACT
AIM:
The current study examined symptoms of irritation reported by non-smokers passively exposed to e-cigarette aerosols and their timing and association with the concentrations of volatile organic compounds (VOCs) produced.METHODS:
40 healthy non-smoking adults were exposed to e-cigarette aerosols for 30â¯min in a 35â¯m3 room. Second-hand e-cigarette aerosol (SHA) was produced by an experienced e-cigarette user using a standardized topography and two resistance settings (exposure 0.5 Ohm and 1.5 Ohm), in addition to a control session (no emissions). PM2.5 and PM1.0 were continuously measured over the duration of exposure, while Volatile Organic Compounds (VOCs) were recorded at 0, 15 and 30â¯min (t0, t15 and t30) of exposure. Each participant completed an irritation questionnaire at t0, t15, t30 of exposure and t60 (30â¯min post-exposure) on ocular, nasal, throat-respiratory symptoms of irritation and general complaints. Kruskal-Wallis H test for PM comparisons, repeated measures ANOVA for VOCs and Generalized Estimating Equations for symptoms of irritation and association with VOCs were used for statistical analysis.RESULTS:
20 males and 20 females, with a mean age of 24.6 years (SDâ¯=â¯4.3) and exhaled COâ¯<â¯7â¯ppm participated. PM concentrations in both experimental sessions were higher than the Control (pâ¯<â¯0.001). The most commonly reported symptoms were burning, dryness, sore throat, cough, breathlessness and headache. During both experimental sessions, ocular, nasal, throat-respiratory symptoms and general complaints increased significantly (pâ¯<â¯0.05). Ocular and nasal symptoms returned to baseline by t60 (pâ¯>â¯0.05) while throat-respiratory symptoms were still significantly higher at t60 (pâ¯=â¯0.044). VOCs were significantly associated with reported nasal and throat-respiratory symptoms in both experimental sessions (pâ¯<â¯0.05).CONCLUSION:
A 30-min exposure to SHA provoked symptoms of sensory irritation and general complaints that lasted up to 30â¯min after the exposure and were positively associated with the concentrations of the VOC mixture emitted.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Contaminación por Humo de Tabaco
/
Contaminantes Atmosféricos
/
Compuestos Orgánicos Volátiles
/
Sistemas Electrónicos de Liberación de Nicotina
Tipo de estudio:
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Environ Res
Año:
2020
Tipo del documento:
Article
País de afiliación:
Grecia