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Development of selective mono or dual PROTAC degrader probe of CDK isoforms.
Zhou, Fei; Chen, Luyu; Cao, Chaoguo; Yu, Jiang; Luo, Xiaojiao; Zhou, Peiting; Zhao, Lifeng; Du, Wu; Cheng, Jijun; Xie, Yongmei; Chen, Yuanwei.
Afiliación
  • Zhou F; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, 610041, China.
  • Chen L; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, 610041, China.
  • Cao C; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, 610041, China.
  • Yu J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, 610041, China.
  • Luo X; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, 610041, China.
  • Zhou P; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, 610041, China.
  • Zhao L; Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu, 610052, China.
  • Du W; Hinova Pharmaceuticals Inc, 4th Floor, Building RongYao A, No. 5, Keyuan South Road, Chengdu, 610041, China.
  • Cheng J; Hinova Pharmaceuticals Inc, 4th Floor, Building RongYao A, No. 5, Keyuan South Road, Chengdu, 610041, China.
  • Xie Y; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, 610041, China.
  • Chen Y; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, 610041, China; Hinova Pharmaceuticals Inc, 4th Floor, Building RongYao A, No. 5, Keyuan South Road, Chengdu, 610041, China. Electronic address: yw
Eur J Med Chem ; 187: 111952, 2020 Feb 01.
Article en En | MEDLINE | ID: mdl-31846828
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Quinasas Ciclina-Dependientes / Inhibidores de Proteínas Quinasas / Proteolisis Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2020 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Quinasas Ciclina-Dependientes / Inhibidores de Proteínas Quinasas / Proteolisis Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2020 Tipo del documento: Article País de afiliación: China