Comparative study on the replication of HCV1b genome between wild-type and cell culture-adaptive mutant in regard to sensitivities against anti-HCV drugs.

Miyayama, Yohei; Lee, Heini; Song, HoJoong; Abe-Chayama, Hiromi; Miki, Daiki; Imamura, Michio; Chayama, Kazuaki; Hijikata, Makoto

Miyayama, Yohei; Lee, Heini; Song, HoJoong; Abe-Chayama, Hiromi; Miki, Daiki; Imamura, Michio; Chayama, Kazuaki; Hijikata, Makoto.

Afiliación

Miyayama Y; Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Lee H; Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
Song H; Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Abe-Chayama H; Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
Miki D; Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Imamura M; Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
Chayama K; Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.
Hijikata M; Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.

Microbiol Immunol ; 64(4): 296-303, 2020 Apr.

Article en En | MEDLINE | ID: mdl-31854467

Asunto(s)

Farmacorresistencia Viral; Hepacivirus/fisiología; Replicación Viral; Antivirales/farmacología; Línea Celular; Genoma Viral; Hepacivirus/genética; Humanos; Mutación; Replicón

Palabras clave

HCV1b; KT9; SEC14L2; anti-HCV; cell culture-adaptive mutation; subgenomic replicon

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Replicación Viral / Hepacivirus / Farmacorresistencia Viral Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Microbiol Immunol Año: 2020 Tipo del documento: Article País de afiliación: Japón

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