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Inhaled amikacin adjunctive to intravenous standard-of-care antibiotics in mechanically ventilated patients with Gram-negative pneumonia (INHALE): a double-blind, randomised, placebo-controlled, phase 3, superiority trial.
Niederman, Michael S; Alder, Jeff; Bassetti, Matteo; Boateng, Francis; Cao, Bin; Corkery, Kevin; Dhand, Rajiv; Kaye, Keith S; Lawatscheck, Robert; McLeroth, Patrick; Nicolau, David P; Wang, Chen; Wood, G Christopher; Wunderink, Richard G; Chastre, Jean.
Afiliación
  • Niederman MS; Division of Pulmonary and Critical Care Medicine, New York Presbyterian/Weill Cornell Medical Center, New York, NY, USA. Electronic address: msn9004@med.cornell.edu.
  • Alder J; Anti-Infective Consulting, Margaretville, NY, USA.
  • Bassetti M; Infectious Diseases Clinic, Department of Health Sciences, University of Genoa and Policlinico San Martino Hospital, Genoa, Italy; Department of Health Sciences, University of Genoa, Genoa, Italy.
  • Boateng F; Bayer Healthcare Inc, Whippany, NJ, USA.
  • Cao B; Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China.
  • Corkery K; Novartis Pharmaceuticals, San Carlos, CA, USA.
  • Dhand R; Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN, USA.
  • Kaye KS; Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
  • Lawatscheck R; Bayer AG, Berlin, Germany.
  • McLeroth P; Covance, Princeton, NJ, USA.
  • Nicolau DP; Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, CT, USA.
  • Wang C; Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China.
  • Wood GC; Department of Clinical Pharmacy and Translational Science, University of Tennessee Health Science Center, University of Tennessee, Memphis, TN, USA.
  • Wunderink RG; Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Chastre J; Intensive Care Unit, Sorbonne University Hospitals, Paris, France.
Lancet Infect Dis ; 20(3): 330-340, 2020 03.
Article en En | MEDLINE | ID: mdl-31866328
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Administración por Inhalación / Amicacina / Infecciones por Bacterias Gramnegativas / Neumonía Asociada al Ventilador / Antibacterianos Tipo de estudio: Clinical_trials / Guideline / Observational_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2020 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Administración por Inhalación / Amicacina / Infecciones por Bacterias Gramnegativas / Neumonía Asociada al Ventilador / Antibacterianos Tipo de estudio: Clinical_trials / Guideline / Observational_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2020 Tipo del documento: Article