CYPs-mediated drug-drug interactions on psoralidin, isobavachalcone, neobavaisoflavone and daidzein in rats liver microsomes.

Shi, Mengjun; Cui, Yiping; Liu, Cunyu; Li, Changqin; Liu, Zhenhua; Kang, Wen-Yi

Shi, Mengjun; Cui, Yiping; Liu, Cunyu; Li, Changqin; Liu, Zhenhua; Kang, Wen-Yi.

Afiliación

Shi M; National R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng, 475004, China.
Cui Y; National R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng, 475004, China.
Liu C; National R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng, 475004, China; Joint International Research Laboratory of Food & Medicine, Henan Province, Henan University, Kaifeng, 475004, China.
Li C; National R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng, 475004, China; Kaifeng Key Laboratory of Functional Components in Health Food, Kaifeng, 475004, Henan, China.
Liu Z; National R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng, 475004, China. Electronic address: liuzhenhua623@163.com.
Kang WY; National R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng, 475004, China; Joint International Research Laboratory of Food & Medicine, Henan Province, Henan University, Kaifeng, 475004, China. Electronic address: kangweny@hotmail.com.

Food Chem Toxicol ; 136: 111027, 2020 Feb.

Article en En | MEDLINE | ID: mdl-31870919

Asunto(s)

Benzofuranos/toxicidad; Chalconas/toxicidad; Cumarinas/toxicidad; Citocromo P-450 CYP2E1/metabolismo; Citocromo P-450 CYP3A/metabolismo; Isoflavonas/toxicidad; Microsomas Hepáticos/metabolismo; Animales; Benzofuranos/metabolismo; Chalconas/metabolismo; Cumarinas/metabolismo; Inhibidores del Citocromo P-450 CYP2E1/metabolismo; Inhibidores del Citocromo P-450 CYP2E1/toxicidad; Inhibidores del Citocromo P-450 CYP3A/metabolismo; Inhibidores del Citocromo P-450 CYP3A/toxicidad; Interacciones Farmacológicas; Isoflavonas/metabolismo; Ratas Sprague-Dawley

Palabras clave

CYP2E1; CYP3A4; Compounds; DDIs; Fructus psoraleae

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Benzofuranos / Microsomas Hepáticos / Citocromo P-450 CYP2E1 / Cumarinas / Chalconas / Citocromo P-450 CYP3A / Isoflavonas Tipo de estudio: Guideline Límite: Animals Idioma: En Revista: Food Chem Toxicol Año: 2020 Tipo del documento: Article País de afiliación: China

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