miR-200b/c-RAP1B axis represses tumorigenesis and malignant progression of papillary thyroid carcinoma through inhibiting the NF-&#954;B/Twist1 pathway.

Zhou, Bo; Xu, Jing; Chen, Ye; Gao, Shegan; Feng, Xiaoshan; Lu, Xiubo

miR-200b/c-RAP1B axis represses tumorigenesis and malignant progression of papillary thyroid carcinoma through inhibiting the NF-κB/Twist1 pathway.

Zhou, Bo; Xu, Jing; Chen, Ye; Gao, Shegan; Feng, Xiaoshan; Lu, Xiubo.

Afiliación

Zhou B; Department of General Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, PR China; Department of Oncology Surgery, The First Affiliated Hospital and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, 471003, Henan, PR China.
Xu J; Department of Gynaecology and Obstetrics, The Third Affiliated Hospital of Henan University of Science and Technology, Luoyang, 471003, Henan, PR China.
Chen Y; Department of Oncology Surgery, The First Affiliated Hospital and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, 471003, Henan, PR China.
Gao S; Department of Oncology Surgery, The First Affiliated Hospital and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, 471003, Henan, PR China.
Feng X; Department of Oncology Surgery, The First Affiliated Hospital and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, 471003, Henan, PR China.
Lu X; Department of General Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, PR China. Electronic address: Luxiubo8866@163.com.

Exp Cell Res ; 387(2): 111785, 2020 02 15.

Article en En | MEDLINE | ID: mdl-31877303

Asunto(s)

Carcinogénesis/genética; MicroARNs/genética; FN-kappa B/genética; Proteínas Nucleares/genética; Cáncer Papilar Tiroideo/genética; Neoplasias de la Tiroides/genética; Proteína 1 Relacionada con Twist/genética; Proteínas de Unión al GTP rap/genética; Animales; Línea Celular; Movimiento Celular/genética; Proliferación Celular/genética; Femenino; Regulación Neoplásica de la Expresión Génica/genética; Células HEK293; Humanos; Ratones; Ratones Endogámicos BALB C; Ratones Desnudos; Transducción de Señal/genética; Cáncer Papilar Tiroideo/patología; Neoplasias de la Tiroides/patología; Regulación hacia Arriba/genética

Palabras clave

EMT; Papillary thyroid carcinoma; RAP1B; Twist1/NF-κB pathway; miR-200b/C

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias de la Tiroides / Proteínas Nucleares / FN-kappa B / Proteínas de Unión al GTP rap / MicroARNs / Proteína 1 Relacionada con Twist / Carcinogénesis / Cáncer Papilar Tiroideo Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Exp Cell Res Año: 2020 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google