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Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma.
Noorani, Ayesha; Li, Xiaodun; Goddard, Martin; Crawte, Jason; Alexandrov, Ludmil B; Secrier, Maria; Eldridge, Matthew D; Bower, Lawrence; Weaver, Jamie; Lao-Sirieix, Pierre; Martincorena, Inigo; Debiram-Beecham, Irene; Grehan, Nicola; MacRae, Shona; Malhotra, Shalini; Miremadi, Ahmad; Thomas, Tabitha; Galbraith, Sarah; Petersen, Lorraine; Preston, Stephen D; Gilligan, David; Hindmarsh, Andrew; Hardwick, Richard H; Stratton, Michael R; Wedge, David C; Fitzgerald, Rebecca C.
Afiliación
  • Noorani A; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Li X; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Goddard M; Department of Histopathology, Papworth Hospital NHS Trust, Cambridge, UK.
  • Crawte J; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Alexandrov LB; Cellular and Molecular Medicine, University of California, San Diego, San Diego, CA, USA.
  • Secrier M; Cancer Research UK Cambridge Research Institute, Cambridge, UK.
  • Eldridge MD; Cancer Research UK Cambridge Research Institute, Cambridge, UK.
  • Bower L; Cancer Research UK Cambridge Research Institute, Cambridge, UK.
  • Weaver J; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Lao-Sirieix P; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Martincorena I; Wellcome Trust Sanger Institute, Cambridge, UK.
  • Debiram-Beecham I; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Grehan N; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • MacRae S; MRC Cancer Unit, University of Cambridge, Cambridge, UK.
  • Malhotra S; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Miremadi A; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Thomas T; Arthur Rank Hospice Charity, Cambridge, UK.
  • Galbraith S; Department of Palliative Care, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Petersen L; Arthur Rank Hospice Charity, Cambridge, UK.
  • Preston SD; Department of Histopathology, Papworth Hospital NHS Trust, Cambridge, UK.
  • Gilligan D; Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Hindmarsh A; Cambridge Oesophago-Gastric Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Hardwick RH; Cambridge Oesophago-Gastric Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Stratton MR; Wellcome Trust Sanger Institute, Cambridge, UK.
  • Wedge DC; Big Data Institute, University of Oxford, Oxford, UK. david.wedge@bdi.ox.ac.uk.
  • Fitzgerald RC; Oxford NIHR Biomedical Research Centre, Oxford, UK. david.wedge@bdi.ox.ac.uk.
Nat Genet ; 52(1): 74-83, 2020 01.
Article en En | MEDLINE | ID: mdl-31907488
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Adenocarcinoma / Modelos Estadísticos / Genómica / Evolución Clonal Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Humans / Male / Middle aged Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Adenocarcinoma / Modelos Estadísticos / Genómica / Evolución Clonal Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Humans / Male / Middle aged Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido