Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development.

Daniel, Edward; Barlow, Haley R; Sutton, Gabrielle I; Gu, Xiaowu; Htike, Yadanar; Cowdin, Mitzy A; Cleaver, Ondine

Daniel, Edward; Barlow, Haley R; Sutton, Gabrielle I; Gu, Xiaowu; Htike, Yadanar; Cowdin, Mitzy A; Cleaver, Ondine.

Afiliación

Daniel E; Department of Molecular Biology and Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Barlow HR; Department of Molecular Biology and Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Sutton GI; Department of Molecular Biology and Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Gu X; Department of Molecular Biology and Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Htike Y; Department of Molecular Biology and Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Cowdin MA; Department of Molecular Biology and Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Cleaver O; Department of Molecular Biology and Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA ondine.cleaver@utsouthwestern.edu.

Development ; 147(4)2020 02 20.

Article en En | MEDLINE | ID: mdl-32001436

Asunto(s)

Epitelio/embriología; Pulmón/embriología; Alveolos Pulmonares/embriología; Ácido Retinoico 4-Hidroxilasa/genética; Ácido Retinoico 4-Hidroxilasa/fisiología; Animales; Sistemas CRISPR-Cas; Diferenciación Celular; Células Endoteliales/citología; Células Epiteliales/citología; Femenino; Regulación del Desarrollo de la Expresión Génica; Riñón/embriología; Ratones; Ratones Endogámicos C57BL; Organogénesis/efectos de los fármacos; Embarazo; Preñez; Transducción de Señal; Células Madre/citología; Tretinoina/farmacología

Palabras clave

Cyp26b1; Endothelial cell; Epithelial cell; Epithelium; Lung; Mouse; Retinoic acid

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Alveolos Pulmonares / Epitelio / Ácido Retinoico 4-Hidroxilasa / Pulmón Límite: Animals / Pregnancy Idioma: En Revista: Development Asunto de la revista: BIOLOGIA / EMBRIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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