Case Report of Increased Exposure to Antiretrovirals following Sleeve Gastrectomy.
Antimicrob Agents Chemother
; 64(4)2020 03 24.
Article
en En
| MEDLINE
| ID: mdl-32015045
ABSTRACT
Bariatric surgery is increasingly performed in morbidly obese HIV patients. Limited data exist regarding antiretroviral drug exposure after bariatric surgery. We report a case of a morbidly obese HIV patient who underwent sleeve gastrectomy. Abacavir, lamivudine, and dolutegravir therapeutic drug monitoring was performed at several time points pre- and postsurgery. Significantly increased levels were measured, particularly for abacavir, whose levels increased â¼12-fold. Several mechanistic explanations for these findings are discussed.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Obesidad Mórbida
/
Antirretrovirales
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Cirugía Bariátrica
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Gastrectomía
Límite:
Adult
/
Humans
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Male
Idioma:
En
Revista:
Antimicrob Agents Chemother
Año:
2020
Tipo del documento:
Article
País de afiliación:
Israel