MicroRNA biomarkers for chemical hazard screening identified by RNA deep sequencing analysis in mouse embryonic stem cells.

Aoki, Hiroshi; Tani, Hidenori; Nakamura, Kaoru; Sato, Hiroaki; Torimura, Masaki; Nakazato, Tetsuya

Aoki, Hiroshi; Tani, Hidenori; Nakamura, Kaoru; Sato, Hiroaki; Torimura, Masaki; Nakazato, Tetsuya.

Afiliación

Aoki H; Environmental Management Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 16-1 Onogawa, Tsukuba, Ibaraki 305-8569, Japan. Electronic address: aoki-h@aist.go.jp.
Tani H; Environmental Management Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 16-1 Onogawa, Tsukuba, Ibaraki 305-8569, Japan.
Nakamura K; Environmental Management Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 16-1 Onogawa, Tsukuba, Ibaraki 305-8569, Japan.
Sato H; Research Institute of Sustainable Chemistry, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan.
Torimura M; Environmental Management Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 16-1 Onogawa, Tsukuba, Ibaraki 305-8569, Japan.
Nakazato T; Environmental Management Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 16-1 Onogawa, Tsukuba, Ibaraki 305-8569, Japan.

Toxicol Appl Pharmacol ; 392: 114929, 2020 04 01.

Article en En | MEDLINE | ID: mdl-32105654

Asunto(s)

Células Madre Embrionarias/efectos de los fármacos; Células Madre Embrionarias/metabolismo; Sustancias Peligrosas/toxicidad; MicroARNs/metabolismo; Análisis de Secuencia de ARN/métodos; Animales; Biomarcadores; Sustancias Peligrosas/química; Ratones; Estructura Molecular; Pruebas de Toxicidad

Palabras clave

Chemical toxicity; Deep sequencing analysis; Non-coding RNAs; RNA biomarkers; RNA-seq; microRNAs (miRNAs)

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sustancias Peligrosas / Análisis de Secuencia de ARN / MicroARNs / Células Madre Embrionarias Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Animals Idioma: En Revista: Toxicol Appl Pharmacol Año: 2020 Tipo del documento: Article

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