Protective Effect of Low-Molecular-Weight Fucoidan on Radiation-Induced Fibrosis Through TGF-ß1/Smad Pathway-Mediated Inhibition of Collagen I Accumulation.

Wu, Szu-Yuan; Chen, Yu-Ting; Tsai, Guo-Yu; Hsu, Fu-Yin; Hwang, Pai-An

Wu, Szu-Yuan; Chen, Yu-Ting; Tsai, Guo-Yu; Hsu, Fu-Yin; Hwang, Pai-An.

Afiliación

Wu SY; Department of Food Nutrition and Health Biotechnology, College of Medical and Health Science, Asia University, Taichung 413, Taiwan.
Chen YT; Division of Radiation Oncology, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Yilan 265, Taiwan.
Tsai GY; Department of Radiation Oncology, Wan Fang Hospital, Taipei Medical University, Taipei 116, Taiwan..
Hsu FY; Big Data Center, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Yilan 265, Taiwan.
Hwang PA; Department of Healthcare Administration, College of Medical and Health Science, Asia University, Taichung 413, Taiwan.

Mar Drugs ; 18(3)2020 Feb 27.

Article en En | MEDLINE | ID: mdl-32120789

Asunto(s)

Polisacáridos/farmacología; Sustancias Protectoras/farmacología; Neumonitis por Radiación/prevención & control; Animales; Colágeno/metabolismo; Ratones; Células 3T3 NIH/efectos de los fármacos; Transducción de Señal; Proteína smad3/metabolismo; Factor de Crecimiento Transformador beta/metabolismo

Palabras clave

Smad pathway; TGF-ß1; collagen I; low-molecular-weight fucoidan; radiation-induced fibrosis

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Polisacáridos / Neumonitis por Radiación / Sustancias Protectoras Límite: Animals Idioma: En Revista: Mar Drugs Asunto de la revista: BIOLOGIA / FARMACOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Taiwán

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