Microtubule associated protein 9 inhibits liver tumorigenesis by suppressing ERCC3.

Zhang, Jing; Huang, Jun-Zhe; Zhang, Yan-Quan; Zhang, Xiang; Zhao, Liu-Yang; Li, Chuan-Gen; Zhou, Yun-Fei; Wei, Hong; Yu, Jun

Zhang, Jing; Huang, Jun-Zhe; Zhang, Yan-Quan; Zhang, Xiang; Zhao, Liu-Yang; Li, Chuan-Gen; Zhou, Yun-Fei; Wei, Hong; Yu, Jun.

Afiliación

Zhang J; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong; Department of Gastroenterology, Shanghai Jiao Tong University
Huang JZ; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong.
Zhang YQ; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong.
Zhang X; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong.
Zhao LY; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong.
Li CG; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong.
Zhou YF; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong.
Wei H; Center of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yu J; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong. Electronic address: junyu@cuhk.edu.hk.

EBioMedicine ; 53: 102701, 2020 Mar.

Article en En | MEDLINE | ID: mdl-32151798

Asunto(s)

Biomarcadores de Tumor/genética; Carcinogénesis/genética; Carcinoma Hepatocelular/metabolismo; ADN Helicasas/genética; Proteínas de Unión al ADN/genética; Neoplasias Hepáticas/metabolismo; Proteínas Asociadas a Microtúbulos/genética; Animales; Biomarcadores de Tumor/metabolismo; Carcinogénesis/metabolismo; Carcinogénesis/patología; Carcinoma Hepatocelular/genética; Carcinoma Hepatocelular/patología; Movimiento Celular; Proliferación Celular; ADN Helicasas/metabolismo; Proteínas de Unión al ADN/metabolismo; Regulación hacia Abajo; Silenciador del Gen; Células Hep G2; Hepatocitos/metabolismo; Hepatocitos/fisiología; Humanos; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/patología; Ratones; Ratones Endogámicos C57BL; Proteínas Asociadas a Microtúbulos/metabolismo; Células Tumorales Cultivadas

Palabras clave

ERCC3; Hepatocellular Carcinoma; Microtubule associated protein 9; Promoter methylation

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Biomarcadores de Tumor / ADN Helicasas / Carcinoma Hepatocelular / Proteínas de Unión al ADN / Carcinogénesis / Neoplasias Hepáticas / Proteínas Asociadas a Microtúbulos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: EBioMedicine Año: 2020 Tipo del documento: Article

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