Humanin analogue, HNG, inhibits platelet activation and thrombus formation by stabilizing platelet microtubules.

Ren, Lijie; Li, Qing; You, Tao; Zhao, Xuefei; Xu, Xingshun; Tang, Chaojun; Zhu, Li

Ren, Lijie; Li, Qing; You, Tao; Zhao, Xuefei; Xu, Xingshun; Tang, Chaojun; Zhu, Li.

Afiliación

Ren L; Suzhou Key Laboratory of Thrombosis and Vascular Diseases, State Key Laboratory of Radiation Medicine and Protection, Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology of Jiangsu Province, Soochow University, Suzhou, China.
Li Q; Suzhou Key Laboratory of Thrombosis and Vascular Diseases, State Key Laboratory of Radiation Medicine and Protection, Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology of Jiangsu Province, Soochow University, Suzhou, China.
You T; Suzhou Key Laboratory of Thrombosis and Vascular Diseases, State Key Laboratory of Radiation Medicine and Protection, Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology of Jiangsu Province, Soochow University, Suzhou, China.
Zhao X; Suzhou Key Laboratory of Thrombosis and Vascular Diseases, State Key Laboratory of Radiation Medicine and Protection, Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology of Jiangsu Province, Soochow University, Suzhou, China.
Xu X; The Institute of Neuroscience, Soochow University, Suzhou, China.
Tang C; Suzhou Key Laboratory of Thrombosis and Vascular Diseases, State Key Laboratory of Radiation Medicine and Protection, Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology of Jiangsu Province, Soochow University, Suzhou, China.
Zhu L; Suzhou Key Laboratory of Thrombosis and Vascular Diseases, State Key Laboratory of Radiation Medicine and Protection, Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology of Jiangsu Province, Soochow University, Suzhou, China.

J Cell Mol Med ; 24(8): 4773-4783, 2020 04.

Article en En | MEDLINE | ID: mdl-32174022

Asunto(s)

Histona Desacetilasa 6/genética; Péptidos y Proteínas de Señalización Intracelular/genética; Trombosis/tratamiento farmacológico; Adenosina Trifosfato/genética; Animales; Coagulación Sanguínea/efectos de los fármacos; Coagulación Sanguínea/genética; Plaquetas/efectos de los fármacos; Plaquetas/metabolismo; Humanos; Péptidos y Proteínas de Señalización Intracelular/farmacología; Ratones; Microtúbulos/genética; Microtúbulos/metabolismo; Selectina-P/genética; Activación Plaquetaria/efectos de los fármacos; Activación Plaquetaria/genética; Agregación Plaquetaria/efectos de los fármacos; Transducción de Señal/efectos de los fármacos; Trombosis/genética; Trombosis/patología

Palabras clave

humanin; microtubule; platelet activation; platelet aggregation; thrombus formation

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Trombosis / Péptidos y Proteínas de Señalización Intracelular / Histona Desacetilasa 6 Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Cell Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article País de afiliación: China

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