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Antisense Oligonucleotide in LNA-Gapmer Design Targeting TGFBR2-A Key Single Gene Target for Safe and Effective Inhibition of TGFß Signaling.
Kuespert, Sabrina; Heydn, Rosmarie; Peters, Sebastian; Wirkert, Eva; Meyer, Anne-Louise; Siebörger, Mareile; Johannesen, Siw; Aigner, Ludwig; Bogdahn, Ulrich; Bruun, Tim-Henrik.
Afiliación
  • Kuespert S; Department of Neurology, University Hospital of Regensburg, 93053 Regensburg, Germany.
  • Heydn R; Department of Neurology, University Hospital of Regensburg, 93053 Regensburg, Germany.
  • Peters S; Department of Neurology, University Hospital of Regensburg, 93053 Regensburg, Germany.
  • Wirkert E; Department of Neurology, University Hospital of Regensburg, 93053 Regensburg, Germany.
  • Meyer AL; Department of Neurology, University Hospital of Regensburg, 93053 Regensburg, Germany.
  • Siebörger M; Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Freiburg, 79104 Freiburg, Germany.
  • Johannesen S; Department of Neurology, University Hospital of Regensburg, 93053 Regensburg, Germany.
  • Aigner L; Department of Neurology, University Hospital of Regensburg, 93053 Regensburg, Germany.
  • Bogdahn U; Institute for Regenerative Medicine, Spinal Cord Injury and Tissue Regeneration Center Salzburg, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria.
  • Bruun TH; Velvio GmbH, Am Biopark 11, 93053 Regensburg, Germany.
Int J Mol Sci ; 21(6)2020 Mar 12.
Article en En | MEDLINE | ID: mdl-32178467
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oligonucleótidos / Transducción de Señal / Oligonucleótidos Antisentido / Receptor Tipo II de Factor de Crecimiento Transformador beta Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oligonucleótidos / Transducción de Señal / Oligonucleótidos Antisentido / Receptor Tipo II de Factor de Crecimiento Transformador beta Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: Alemania