The role of glycosaminoglycans in the management of chronic pelvic pain: a systematic review.
Minerva Urol Nefrol
; 72(3): 321-331, 2020 Jun.
Article
en En
| MEDLINE
| ID: mdl-32182229
ABSTRACT
INTRODUCTION:
Glycosaminoglycans (GAGs) are involved in the pathogenesis of several urologic chronic diseases. Thus, GAGs replenishment therapy is widely reported as a therapeutic tool for chronic pelvic pain (CPP) conditions such as interstitial cystitis/bladder pain syndrome (IC/BPS) and prostate pain syndrome/chronic prostatitis. In this article we reviewed the current status of evidence on the clinic applications of glycosaminoglycans (GAGs) in the CPP. EVIDENCE ACQUISITION A literature search from inception was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis statement to identify clinical trials, randomized controlled trials, meta-analyses, and guidelines. EVIDENCESYNTHESIS:
A total of 29 papers were identified regarding the use of GAGs in CPP.CONCLUSIONS:
GAGs replenishment therapy results are encouraging in chronic forms of pelvic pain even though well-powered randomized clinical trials are needed to better comprehend the exact role of this treatment.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Dolor Pélvico
/
Dolor Crónico
/
Glicosaminoglicanos
Tipo de estudio:
Clinical_trials
/
Guideline
/
Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
Minerva Urol Nefrol
Asunto de la revista:
NEFROLOGIA
/
UROLOGIA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Italia