Pharmacokinetic analysis for model-supported therapeutic drug monitoring of busulfan in Japanese pediatric hematopoietic stem cell transplantation recipients.

Kishimoto, Kenji; Hasegawa, Daiichiro; Irie, Kei; Okada, Akira; Nakamura, Sayaka; Tamura, Akihiro; Yamamoto, Nobuyuki; Kozaki, Aiko; Saito, Atsuro; Ishida, Toshiaki; Fukushima, Shoji; Kosaka, Yoshiyuki

Kishimoto, Kenji; Hasegawa, Daiichiro; Irie, Kei; Okada, Akira; Nakamura, Sayaka; Tamura, Akihiro; Yamamoto, Nobuyuki; Kozaki, Aiko; Saito, Atsuro; Ishida, Toshiaki; Fukushima, Shoji; Kosaka, Yoshiyuki.

Afiliación

Kishimoto K; Department of Hematology & Oncology, Children's Cancer Center, Kobe Children's Hospital, Kobe, Japan.
Hasegawa D; Department of Hematology & Oncology, Children's Cancer Center, Kobe Children's Hospital, Kobe, Japan.
Irie K; Department of Clinical Pharmacy, Faculty of Pharmaceutical Science, Kobe Gakuin University, Kobe, Japan.
Okada A; Department of Pharmacy, Kobe City Hospital Organization Kobe City Medical Center General Hospital, Kobe, Japan.
Nakamura S; Department of Regulatory Science, Faculty of Pharmacy, Musashino University, Tokyo, Japan.
Tamura A; Department of Hematology & Oncology, Children's Cancer Center, Kobe Children's Hospital, Kobe, Japan.
Yamamoto N; Department of Hematology & Oncology, Children's Cancer Center, Kobe Children's Hospital, Kobe, Japan.
Kozaki A; Department of Hematology & Oncology, Children's Cancer Center, Kobe Children's Hospital, Kobe, Japan.
Saito A; Department of Hematology & Oncology, Children's Cancer Center, Kobe Children's Hospital, Kobe, Japan.
Ishida T; Department of Hematology & Oncology, Children's Cancer Center, Kobe Children's Hospital, Kobe, Japan.
Fukushima S; Department of Hematology & Oncology, Children's Cancer Center, Kobe Children's Hospital, Kobe, Japan.
Kosaka Y; Department of Clinical Pharmacy, Faculty of Pharmaceutical Science, Kobe Gakuin University, Kobe, Japan.

Pediatr Transplant ; 24(4): e13696, 2020 06.

Article en En | MEDLINE | ID: mdl-32196880

Asunto(s)

Busulfano/farmacocinética; Monitoreo de Drogas/métodos; Trasplante de Células Madre Hematopoyéticas; Agonistas Mieloablativos/farmacocinética; Acondicionamiento Pretrasplante/métodos; Niño; Preescolar; Femenino; Humanos; Japón; Masculino; Modelos Teóricos; Estudios Prospectivos

Palabras clave

busulfan; hematopoietic stem cell transplantation; model; pediatric; population pharmacokinetics

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Busulfano / Monitoreo de Drogas / Trasplante de Células Madre Hematopoyéticas / Acondicionamiento Pretrasplante / Agonistas Mieloablativos Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Child / Child, preschool / Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: Pediatr Transplant Asunto de la revista: PEDIATRIA / TRANSPLANTE Año: 2020 Tipo del documento: Article País de afiliación: Japón

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