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Quantifying Target Occupancy of Small Molecules Within Living Cells.
Robers, M B; Friedman-Ohana, R; Huber, K V M; Kilpatrick, L; Vasta, J D; Berger, B-T; Chaudhry, C; Hill, S; Müller, S; Knapp, S; Wood, K V.
Afiliación
  • Robers MB; Promega Corporation, Madison, Wisconsin 53711, USA; email: matt.robers@promega.com, rachel.ohana@promega.com, jim.vasta@promega.com.
  • Friedman-Ohana R; Promega Corporation, Madison, Wisconsin 53711, USA; email: matt.robers@promega.com, rachel.ohana@promega.com, jim.vasta@promega.com.
  • Huber KVM; Target Discovery Institute and Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, United Kingdom; email: kilian.huber@sgc.ox.ac.uk.
  • Kilpatrick L; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom.
  • Vasta JD; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, United Kingdom; email: laura.kilpatrick@nottingham.ac.uk, steve.hill@nottingham.ac.uk.
  • Berger BT; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands NG7 2UH, United Kingdom.
  • Chaudhry C; Promega Corporation, Madison, Wisconsin 53711, USA; email: matt.robers@promega.com, rachel.ohana@promega.com, jim.vasta@promega.com.
  • Hill S; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, 60438 Frankfurt, Germany; email: b.berger@chemie.uni-frankfurt.de, knapp@pharmchem.uni-frankfurt.de.
  • Müller S; Lead Discovery and Optimization, Bristol-Myers Squibb, Princeton, New Jersey 08648, USA; email: charu.chaudhry@bms.com.
  • Knapp S; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, United Kingdom; email: laura.kilpatrick@nottingham.ac.uk, steve.hill@nottingham.ac.uk.
  • Wood KV; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands NG7 2UH, United Kingdom.
Annu Rev Biochem ; 89: 557-581, 2020 06 20.
Article en En | MEDLINE | ID: mdl-32208767
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Química Farmacéutica / Técnicas de Sonda Molecular / Ensayos Analíticos de Alto Rendimiento / Terapia Molecular Dirigida / Colorantes Fluorescentes Límite: Humans Idioma: En Revista: Annu Rev Biochem Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Química Farmacéutica / Técnicas de Sonda Molecular / Ensayos Analíticos de Alto Rendimiento / Terapia Molecular Dirigida / Colorantes Fluorescentes Límite: Humans Idioma: En Revista: Annu Rev Biochem Año: 2020 Tipo del documento: Article