Structural Basis for pri-miRNA Recognition by Drosha.

Jin, Wenxing; Wang, Jia; Liu, Chao-Pei; Wang, Hong-Wei; Xu, Rui-Ming

Jin, Wenxing; Wang, Jia; Liu, Chao-Pei; Wang, Hong-Wei; Xu, Rui-Ming.

Afiliación

Jin W; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Wang J; Ministry of Education Key Laboratory of Protein Sciences, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center of Biological Structures, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Liu CP; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Wang HW; Ministry of Education Key Laboratory of Protein Sciences, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center of Biological Structures, School of Life Sciences, Tsinghua University, Beijing 100084, China. Electro
Xu RM; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; School of Life Sciences, University of the Chinese Academy of Sciences, Beijing 100049, China. Electronic address: rmxu@ibp.ac.cn.

Mol Cell ; 78(3): 423-433.e5, 2020 05 07.

Article en En | MEDLINE | ID: mdl-32220645

Asunto(s)

MicroARNs/química; MicroARNs/metabolismo; Ribonucleasa III/química; Ribonucleasa III/metabolismo; Animales; Microscopía por Crioelectrón; Humanos; Modelos Moleculares; Conformación Proteica; Dominios Proteicos; Proteínas de Unión al ARN/química; Proteínas de Unión al ARN/genética; Proteínas de Unión al ARN/metabolismo; Ribonucleasa III/genética; Spodoptera/citología

Palabras clave

DGCR8; Drosha; Microprocessor; cryo-EM; miRNA; pri-miRNA; structure

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: MicroARNs / Ribonucleasa III Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article País de afiliación: China

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