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Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells.
Kim, Yeonjin; Sundrud, Mark S; Zhou, Changqian; Edenius, Maja; Zocco, Davide; Powers, Kristen; Zhang, Miao; Mazitschek, Ralph; Rao, Anjana; Yeo, Chang-Yeol; Noss, Erika H; Brenner, Michael B; Whitman, Malcolm; Keller, Tracy L.
Afiliación
  • Kim Y; Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115.
  • Sundrud MS; Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL 33458.
  • Zhou C; Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115.
  • Edenius M; Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115.
  • Zocco D; Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115.
  • Powers K; Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115.
  • Zhang M; Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115.
  • Mazitschek R; Center for Systems Biology, Massachusetts General Hospital, Boston, MA 02114.
  • Rao A; Division of Signaling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA 92037.
  • Yeo CY; Department of Life Science, Division of Life and Pharmaceutical Sciences, Ewha Womans University, 03760 Seoul, Korea.
  • Noss EH; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Brenner MB; Division of Rheumatology, Department of Medicine, University of Washington, Seattle, WA 98195.
  • Whitman M; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115; mbrenner@research.bwh.harvard.edu mwhitman@hms.harvard.edu tkeller@hms.harvard.edu.
  • Keller TL; Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115; mbrenner@research.bwh.harvard.edu mwhitman@hms.harvard.edu tkeller@hms.harvard.edu.
Proc Natl Acad Sci U S A ; 117(16): 8900-8911, 2020 04 21.
Article en En | MEDLINE | ID: mdl-32253314
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Piperidinas / Artritis Reumatoide / Transducción de Señal / Quinazolinonas / Aminoacil-ARNt Sintetasas / Antiinflamatorios Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Piperidinas / Artritis Reumatoide / Transducción de Señal / Quinazolinonas / Aminoacil-ARNt Sintetasas / Antiinflamatorios Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article