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Cryo-EM structure of C9ORF72-SMCR8-WDR41 reveals the role as a GAP for Rab8a and Rab11a.
Tang, Dan; Sheng, Jingwen; Xu, Liangting; Zhan, Xiechao; Liu, Jiaming; Jiang, Hui; Shu, Xiaoling; Liu, Xiaoyu; Zhang, Tizhong; Jiang, Lan; Zhou, Cuiyan; Li, Wenqi; Cheng, Wei; Li, Zhonghan; Wang, Kunjie; Lu, Kefeng; Yan, Chuangye; Qi, Shiqian.
Afiliación
  • Tang D; Department of Urology, State Key Laboratory of Biotherapy, West China Hospital, College of Life Sciences, Sichuan University, 610041 Chengdu, China.
  • Sheng J; Department of Urology, State Key Laboratory of Biotherapy, West China Hospital, College of Life Sciences, Sichuan University, 610041 Chengdu, China.
  • Xu L; Department of Urology, State Key Laboratory of Biotherapy, West China Hospital, College of Life Sciences, Sichuan University, 610041 Chengdu, China.
  • Zhan X; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, 10084 Beijing, China.
  • Liu J; Department of Urology, State Key Laboratory of Biotherapy, West China Hospital, College of Life Sciences, Sichuan University, 610041 Chengdu, China.
  • Jiang H; Department of Urology, State Key Laboratory of Biotherapy, West China Hospital, College of Life Sciences, Sichuan University, 610041 Chengdu, China.
  • Shu X; Department of Urology, State Key Laboratory of Biotherapy, West China Hospital, College of Life Sciences, Sichuan University, 610041 Chengdu, China.
  • Liu X; Department of Urology, State Key Laboratory of Biotherapy, West China Hospital, College of Life Sciences, Sichuan University, 610041 Chengdu, China.
  • Zhang T; Department of Urology, State Key Laboratory of Biotherapy, West China Hospital, College of Life Sciences, Sichuan University, 610041 Chengdu, China.
  • Jiang L; Department of Urology, State Key Laboratory of Biotherapy, West China Hospital, College of Life Sciences, Sichuan University, 610041 Chengdu, China.
  • Zhou C; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, 10084 Beijing, China.
  • Li W; State Key Laboratory of Membrane Biology, Tsinghua University, 10084 Beijing, China.
  • Cheng W; Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, 10084 Beijing, China.
  • Li Z; State Key Laboratory of Membrane Biology, Tsinghua University, 10084 Beijing, China.
  • Wang K; Department of Urology, State Key Laboratory of Biotherapy, West China Hospital, College of Life Sciences, Sichuan University, 610041 Chengdu, China.
  • Lu K; Department of Urology, State Key Laboratory of Biotherapy, West China Hospital, College of Life Sciences, Sichuan University, 610041 Chengdu, China.
  • Yan C; Department of Urology, State Key Laboratory of Biotherapy, West China Hospital, College of Life Sciences, Sichuan University, 610041 Chengdu, China.
  • Qi S; Department of Urology, State Key Laboratory of Biotherapy, West China Hospital, College of Life Sciences, Sichuan University, 610041 Chengdu, China.
Proc Natl Acad Sci U S A ; 117(18): 9876-9883, 2020 05 05.
Article en En | MEDLINE | ID: mdl-32303654
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Portadoras / Complejos Multiproteicos / Proteínas Relacionadas con la Autofagia / Proteína C9orf72 Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Portadoras / Complejos Multiproteicos / Proteínas Relacionadas con la Autofagia / Proteína C9orf72 Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article País de afiliación: China