Highly Selective Detection of Metronidazole by Self-Assembly via 0D/2D N-C QDs/g-C3N4 Nanocomposites Through FRET Mechanism.
Nanoscale Res Lett
; 15(1): 87, 2020 Apr 19.
Article
en En
| MEDLINE
| ID: mdl-32307591
ABSTRACT
A 0D/2D (0-dimensional/2-dimensional) nanostructure was designed by self-assembly of N-C QDs and carboxylated g-C3N4 nanosheets and used as a fluorescence resonance energy transfer (FRET) fluorescent sensor. The N-C QDs/g-C3N4 nanosheets were synthesized via the amino group on the N-C QD surface and the -COOH of the carboxylated g-C3N4 nanosheets. The mechanism of detection of metronidazole (MNZ) by N-C QDs/g-C3N4 nanocomposites is based on FRET between negatively charged N-QDs and positively charged carboxylated g-C3N4 nanoparticles. N-C QDs/g-C3N4 nanostructures displayed good responses for the detection of MNZ at normal temperature and pressure. The decrease in the fluorescence intensity showed a good linear relationship to MNZ concentration within 0-2.6 × 10-5 mol/L, and the detection limit was 0.66 µM. The novel FRET sensor will have a great potential in clinical analysis and biological studies.
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Bases de datos:
MEDLINE
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
Nanoscale Res Lett
Año:
2020
Tipo del documento:
Article