In Situ Immune Profiling of Heart Transplant Biopsies Improves Diagnostic Accuracy and Rejection Risk Stratification.

Peyster, Eliot G; Wang, Chichung; Ishola, Felicia; Remeniuk, Bethany; Hoyt, Clifford; Feldman, Michael D; Margulies, Kenneth B

In Situ Immune Profiling of Heart Transplant Biopsies Improves Diagnostic Accuracy and Rejection Risk Stratification.

Peyster, Eliot G; Wang, Chichung; Ishola, Felicia; Remeniuk, Bethany; Hoyt, Clifford; Feldman, Michael D; Margulies, Kenneth B.

Afiliación

Peyster EG; Cardiovascular Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania.
Wang C; Akoya Biosciences, Hopkinton, Massachusetts.
Ishola F; Akoya Biosciences, Hopkinton, Massachusetts.
Remeniuk B; Akoya Biosciences, Hopkinton, Massachusetts.
Hoyt C; Akoya Biosciences, Hopkinton, Massachusetts.
Feldman MD; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Margulies KB; Cardiovascular Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania.

JACC Basic Transl Sci ; 5(4): 328-340, 2020 Apr.

Article en En | MEDLINE | ID: mdl-32368693

Palabras clave

CAR, cardiac allograft rejection; CD, cluster of differentiation; EMB, endomyocardial biopsy; FoxP3, forkhead box P3; H-score, histology score; IF, immunofluorescence; ISHLT, International Society of Heart and Lung Transplantation; PD-L1, programmed death ligand 1; QmIF, quantitative multiplex immunofluorescence; allograft rejection; immune checkpoint molecules; immune regulation; quantitative immunohistochemistry

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Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Idioma: En Revista: JACC Basic Transl Sci Año: 2020 Tipo del documento: Article

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