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RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia.
Shen, Chao; Sheng, Yue; Zhu, Allen C; Robinson, Sean; Jiang, Xi; Dong, Lei; Chen, Huiying; Su, Rui; Yin, Zhe; Li, Wei; Deng, Xiaolan; Chen, Yinhuai; Hu, Yueh-Chiang; Weng, Hengyou; Huang, Huilin; Prince, Emily; Cogle, Christopher R; Sun, Miao; Zhang, Bin; Chen, Chun-Wei; Marcucci, Guido; He, Chuan; Qian, Zhijian; Chen, Jianjun.
Afiliación
  • Shen C; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA.
  • Sheng Y; Department of Medicine and Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL 32608, USA.
  • Zhu AC; Department of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, Medical Scientist Training Program/Committee on Cancer Biology, Howard Hughes Medical Institute, University of Chicago, Chicago, IL 60637, USA.
  • Robinson S; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA.
  • Jiang X; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA; Department of Pharmacology, and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Institute of Hematology, Zhejiang University, and Zhejiang
  • Dong L; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA.
  • Chen H; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA.
  • Su R; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA.
  • Yin Z; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA; Department of Thoracic Surgery, Chongqing Cancer Hospital, Chongqing 400030, China.
  • Li W; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA.
  • Deng X; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA.
  • Chen Y; Transgenic Animal and Genome Editing Facility, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.
  • Hu YC; Transgenic Animal and Genome Editing Facility, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.
  • Weng H; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA.
  • Huang H; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA.
  • Prince E; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA.
  • Cogle CR; Department of Medicine and Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL 32608, USA.
  • Sun M; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
  • Zhang B; Department of Hematologic Malignancies Translational Science, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA.
  • Chen CW; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA.
  • Marcucci G; Department of Hematologic Malignancies Translational Science, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA.
  • He C; Department of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, Medical Scientist Training Program/Committee on Cancer Biology, Howard Hughes Medical Institute, University of Chicago, Chicago, IL 60637, USA. Electronic address: chuanhe@uchicago.edu.
  • Qian Z; Department of Medicine and Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL 32608, USA. Electronic address: zhijian.qian@medicine.ufl.edu.
  • Chen J; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA. Electronic address: jianchen@coh.org.
Cell Stem Cell ; 27(1): 64-80.e9, 2020 07 02.
Article en En | MEDLINE | ID: mdl-32402250
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Autorrenovación de las Células Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cell Stem Cell Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Autorrenovación de las Células Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cell Stem Cell Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos