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Model-Based Analysis Reveals a Sustained and Dose-Dependent Acceleration of Wound Healing by VEGF-A mRNA (AZD8601).
Almquist, Joachim; Rikard, S Michaela; Wågberg, Maria; Bruce, Anthony C; Gennemark, Peter; Fritsche-Danielson, Regina; Chien, Kenneth R; Peirce, Shayn M; Hansson, Kenny; Lundahl, Anna.
Afiliación
  • Almquist J; Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Rikard SM; Fraunhofer-Chalmers Centre, Chalmers Science Park, Gothenburg, Sweden.
  • Wågberg M; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Bruce AC; Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
  • Gennemark P; Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Fritsche-Danielson R; Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
  • Chien KR; Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Peirce SM; Integrative Systems Biology, Department of Biomedical Engineering, Linköping University, Linköping, Sweden.
  • Hansson K; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Lundahl A; Integrated Cardiometabolic Center, Karolinska Institute, Huddinge, Sweden.
CPT Pharmacometrics Syst Pharmacol ; 9(7): 384-394, 2020 07.
Article en En | MEDLINE | ID: mdl-32438492
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Cicatrización de Heridas / ARN Mensajero / Factor A de Crecimiento Endotelial Vascular / Diabetes Mellitus Experimental Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: CPT Pharmacometrics Syst Pharmacol Año: 2020 Tipo del documento: Article País de afiliación: Suecia
Texto completo
Imprimir
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Cicatrización de Heridas / ARN Mensajero / Factor A de Crecimiento Endotelial Vascular / Diabetes Mellitus Experimental Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: CPT Pharmacometrics Syst Pharmacol Año: 2020 Tipo del documento: Article País de afiliación: Suecia