Receptor for advanced glycation end products up-regulation in cerebral endothelial cells mediates cerebrovascular-related amyloid ß accumulation after Porphyromonas gingivalis infection.

Zeng, Fan; Liu, Yicong; Huang, Wanyi; Qing, Hong; Kadowaki, Tomoko; Kashiwazaki, Haruhiko; Ni, Junjun; Wu, Zhou

Zeng, Fan; Liu, Yicong; Huang, Wanyi; Qing, Hong; Kadowaki, Tomoko; Kashiwazaki, Haruhiko; Ni, Junjun; Wu, Zhou.

Afiliación

Zeng F; Department of Aging Science and Pharmacology, Kyushu University, Fukuoka, Japan.
Liu Y; The Affiliated Stomatology Hospital, School of Medical, Zhejiang University, Zhejiang, China.
Huang W; Key Laboratory of Oral Biomedical Research of Zhejiang Province, School of Stomatology, Zhejiang University, Zhejiang, China.
Qing H; Department of Aging Science and Pharmacology, Kyushu University, Fukuoka, Japan.
Kadowaki T; Key Laboratory of Molecular Medicine and Biotherapy in the Ministry of Industry and Information Technology, Department of Biology, School of Life Science, Beijing Institute of Technology, Haidian District, Beijing, China.
Kashiwazaki H; Division of Frontier Life Science, Department of Medical and Dental Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Ni J; Section of Geriatric Dentistry and Perioperative Medicine in Dentistry, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, Fukuoka, Japan.
Wu Z; Department of Aging Science and Pharmacology, Kyushu University, Fukuoka, Japan.

J Neurochem ; 158(3): 724-736, 2021 08.

Article en En | MEDLINE | ID: mdl-32441775

Asunto(s)

Péptidos beta-Amiloides/metabolismo; Infecciones por Bacteroidaceae/metabolismo; Corteza Cerebral/metabolismo; Células Endoteliales/metabolismo; Fragmentos de Péptidos/metabolismo; Porphyromonas gingivalis; Receptor para Productos Finales de Glicación Avanzada/biosíntesis; Animales; Corteza Cerebral/microbiología; Circulación Cerebrovascular/fisiología; Trastornos Cerebrovasculares/metabolismo; Trastornos Cerebrovasculares/microbiología; Células Endoteliales/microbiología; Femenino; Ratones; Ratones Endogámicos C57BL; Regulación hacia Arriba/fisiología

Palabras clave

Porphyromonas gingivalis; NF-κB; amyloid ß; cathepsin B; cerebral endothelial cells; receptor for advanced Glycation end products

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Corteza Cerebral / Péptidos beta-Amiloides / Infecciones por Bacteroidaceae / Porphyromonas gingivalis / Células Endoteliales / Receptor para Productos Finales de Glicación Avanzada Límite: Animals Idioma: En Revista: J Neurochem Año: 2021 Tipo del documento: Article País de afiliación: Japón

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