Antibacterial and cytotoxic activities of cerium oxide nanoparticles prepared by laser ablation in liquid.
Environ Sci Pollut Res Int
; 27(24): 30479-30489, 2020 Aug.
Article
en En
| MEDLINE
| ID: mdl-32468358
ABSTRACT
In this work, we have prepared cerium oxide (CeO2) nanoparticles (NPs) by laser ablation in water at different laser energies. The structural and optical properties of synthesized nanoparticles were characterized by X-ray diffraction (XRD), scanning electron microscope (SEM), Raman spectroscopy, energy dispersive X-ray (EDX), and UV-Vis absorption. XRD results confirmed that the synthesized cerium oxide NPs were crystalline in nature with cubic structure. SEM investigations show that the nanoparticles having a spherical shape with diameter ranged from 26 to 37 nm depending on the laser energy. The antibacterial activity and minimal inhibition concentration of synthesized CeO2 NPs against Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa were examined. Bacterial adhesion test of cerium oxide NPs was also determined under different incubation temperatures. Cytotoxicity of CeO2 NP effect against the human throat cancer was studied. The cytotoxicity effect of CeO2 NPs synthesized at 160 mJ on the cancer cells caused a free radical releasing which causing oxidative stress. The cytotoxicity effects of ceria NPs against human throat cancer (RD rhabdomyosarcoma cell line) and mouse fibroblast L cell (L20B cell line) growth were 33% and 13%, respectively.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Cerio
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Nanopartículas
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Nanopartículas del Metal
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Terapia por Láser
Límite:
Animals
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Humans
Idioma:
En
Revista:
Environ Sci Pollut Res Int
Asunto de la revista:
SAUDE AMBIENTAL
/
TOXICOLOGIA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Irak