[PECULIARITIES OF INTERACTION IN THE "PARASITE-HOST" SYSTEM IN HIV-INFECTED PATIENTS WITH TOXOPLASMOSIS: LITERATURE AND CLINICAL CASE REVIEW].

ABSTRACT

The article presents a review of current literature data on the development of opportunistic toxoplasmosis in patients suffering from HIV infection and a clinical case of an immunocompromised patient with toxoplasmosis. Current information concerning the incidence of toxoplasmosis in Russia and other countries are presented. Special attention is paid to the Toxoplasma gondii interactions with the host cell in HIV-infected people. The mechanism of parasite penetration into the host cell and subsequent modifications that the parasite makes with the occupied cell are analyzed in detail. The significance of the chosen topic is illustrated by the description of a clinical case of toxoplasmosis in an HIV-infected patient. The authors hope that the article will help to attract attention of the professional community to the problem of opportunistic infections in HIV/AIDS carriers, and in particular to the mechanisms of the "parasite-host" interactions in patients with toxoplasmosis.