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Kinase inhibition of G2019S-LRRK2 enhances autolysosome formation and function to reduce endogenous alpha-synuclein intracellular inclusions.
Obergasteiger, Julia; Frapporti, Giulia; Lamonaca, Giulia; Pizzi, Sara; Picard, Anne; Lavdas, Alexandros A; Pischedda, Francesca; Piccoli, Giovanni; Hilfiker, Sabine; Lobbestael, Evy; Baekelandt, Veerle; Hicks, Andrew A; Corti, Corrado; Pramstaller, Peter P; Volta, Mattia.
Afiliación
  • Obergasteiger J; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck - Via Galvani 31, 39100 Bolzano, Italy.
  • Frapporti G; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck - Via Galvani 31, 39100 Bolzano, Italy.
  • Lamonaca G; Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, Via Sommarive 9, 38123 Povo, TN Italy.
  • Pizzi S; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck - Via Galvani 31, 39100 Bolzano, Italy.
  • Picard A; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck - Via Galvani 31, 39100 Bolzano, Italy.
  • Lavdas AA; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck - Via Galvani 31, 39100 Bolzano, Italy.
  • Pischedda F; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck - Via Galvani 31, 39100 Bolzano, Italy.
  • Piccoli G; Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, Via Sommarive 9, 38123 Povo, TN Italy.
  • Hilfiker S; Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, Via Sommarive 9, 38123 Povo, TN Italy.
  • Lobbestael E; Department of Anesthesiology, Rutgers University - New Jersey Medical School, Medical Science Building, 185 South Orange Avenue, Newark, NJ 07103 USA.
  • Baekelandt V; Department of Neurosciences, KU Leuven, Herestraat 49 bus 1023, 3000 Leuven, Belgium.
  • Hicks AA; Department of Neurosciences, KU Leuven, Herestraat 49 bus 1023, 3000 Leuven, Belgium.
  • Corti C; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck - Via Galvani 31, 39100 Bolzano, Italy.
  • Pramstaller PP; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck - Via Galvani 31, 39100 Bolzano, Italy.
  • Volta M; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck - Via Galvani 31, 39100 Bolzano, Italy.
Cell Death Discov ; 6: 45, 2020.
Article en En | MEDLINE | ID: mdl-32550012

Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Cell Death Discov Año: 2020 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Cell Death Discov Año: 2020 Tipo del documento: Article País de afiliación: Italia