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Senolytic CAR T cells reverse senescence-associated pathologies.
Amor, Corina; Feucht, Judith; Leibold, Josef; Ho, Yu-Jui; Zhu, Changyu; Alonso-Curbelo, Direna; Mansilla-Soto, Jorge; Boyer, Jacob A; Li, Xiang; Giavridis, Theodoros; Kulick, Amanda; Houlihan, Shauna; Peerschke, Ellinor; Friedman, Scott L; Ponomarev, Vladimir; Piersigilli, Alessandra; Sadelain, Michel; Lowe, Scott W.
Afiliación
  • Amor C; Louis V. Gerstner Jr Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Feucht J; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Leibold J; Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Ho YJ; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Zhu C; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Alonso-Curbelo D; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Mansilla-Soto J; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Boyer JA; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Li X; Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Giavridis T; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Kulick A; Louis V. Gerstner Jr Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Houlihan S; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Peerschke E; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Friedman SL; Weill Cornell Graduate School of Medical Sciences, New York, NY, USA.
  • Ponomarev V; Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Piersigilli A; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Sadelain M; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Lowe SW; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Nature ; 583(7814): 127-132, 2020 07.
Article en En | MEDLINE | ID: mdl-32555459
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Rejuvenecimiento / Envejecimiento / Linfocitos T / Senescencia Celular / Receptores Quiméricos de Antígenos / Cirrosis Hepática / Longevidad / Neoplasias Pulmonares Tipo de estudio: Risk_factors_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nature Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Rejuvenecimiento / Envejecimiento / Linfocitos T / Senescencia Celular / Receptores Quiméricos de Antígenos / Cirrosis Hepática / Longevidad / Neoplasias Pulmonares Tipo de estudio: Risk_factors_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nature Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos