Vascular morphology and expression of angiogenic factors in sheep ovaries and their relation with the lambing rate.
Reprod Domest Anim
; 55(9): 1132-1138, 2020 Sep.
Article
en En
| MEDLINE
| ID: mdl-32564399
ABSTRACT
The study aims to present the vascular anatomy of ovarian arterial system in sheep and to explore its relation with the angiogenic factors vascular endothelial growth factor (VEGF) and angiopoietin-2 (Ang-2), environmental factors and the lambing rate. Small-tailed Han sheep, Hu sheep, Aohan finewool sheep and Tibetan sheep who are from different habitats in China and with different lambing rates were investigated. The vascular corrosion casting technique and scanning electron microscopy were used to understand arterial architecture, and real-time quantitative PCR (qRT-PCR) and Western blotting were used for assessing VEGF and Ang-2 expression. Results showed that high-prolificity breeds had significantly larger vessel diameters in ovaries than low-prolificity ones. VEGF gene transcript and protein expression were related with the lambing rate, while Ang-2 gene transcript was negatively related with the lambing rate. Results indicated that high-prolificity breeds have more abundant arterial blood supply, which is associated with VEGF expression.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Ovario
/
Oveja Doméstica
Límite:
Animals
País/Región como asunto:
Asia
Idioma:
En
Revista:
Reprod Domest Anim
Asunto de la revista:
MEDICINA REPRODUTIVA
/
MEDICINA VETERINARIA
Año:
2020
Tipo del documento:
Article
País de afiliación:
China