Increased GABAergic development in iPSC-derived neurons from patients with sporadic Alzheimer's disease.

Tang, Yueyu; Han, Yingying; Yu, Hongxiang; Zhang, Bei; Li, Gang

Tang, Yueyu; Han, Yingying; Yu, Hongxiang; Zhang, Bei; Li, Gang.

Afiliación

Tang Y; Department of Neurology, Shanghai East Hospital, Tongji University School of Medicine, 1800 Yuntai Road, Shanghai, 200123, China.
Han Y; Department of Neurology, Shanghai East Hospital, Tongji University School of Medicine, 1800 Yuntai Road, Shanghai, 200123, China.
Yu H; Department of Neurology, Shanghai East Hospital, Tongji University School of Medicine, 1800 Yuntai Road, Shanghai, 200123, China.
Zhang B; Department of Neurology, Shanghai East Hospital, Tongji University School of Medicine, 1800 Yuntai Road, Shanghai, 200123, China. Electronic address: zhangbei0227@163.com.
Li G; Department of Neurology, Shanghai East Hospital, Tongji University School of Medicine, 1800 Yuntai Road, Shanghai, 200123, China. Electronic address: ligang@tongji.edu.cn.

Neurosci Lett ; 735: 135208, 2020 09 14.

Article en En | MEDLINE | ID: mdl-32615251

Asunto(s)

Enfermedad de Alzheimer/metabolismo; Neuronas GABAérgicas/metabolismo; Glutamato Descarboxilasa/metabolismo; Células Madre Pluripotentes Inducidas/metabolismo; Proteínas del Transporte Vesicular de Aminoácidos Inhibidores/metabolismo; Ácido gamma-Aminobutírico/metabolismo; Anciano; Anciano de 80 o más Años; Enfermedad de Alzheimer/patología; Animales; Diferenciación Celular/fisiología; Línea Celular; Femenino; Neuronas GABAérgicas/patología; Humanos; Células Madre Pluripotentes Inducidas/patología; Masculino; Ratones; Persona de Mediana Edad

Palabras clave

Alzheimer's disease; Induced pluripotent stem cells; Neurogenesis; Sporadic; Î³-Aminobutyric acid

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas del Transporte Vesicular de Aminoácidos Inhibidores / Células Madre Pluripotentes Inducidas / Neuronas GABAérgicas / Enfermedad de Alzheimer / Ácido gamma-Aminobutírico / Glutamato Descarboxilasa Límite: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Neurosci Lett Año: 2020 Tipo del documento: Article País de afiliación: China

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