The bacteriology of recurrent acute exacerbations of chronic rhinosinusitis: a longitudinal analysis.
Eur Arch Otorhinolaryngol
; 277(11): 3051-3057, 2020 Nov.
Article
en En
| MEDLINE
| ID: mdl-32623506
ABSTRACT
PURPOSE:
The purpose of this study was to describe the microbiology of recurrent acute exacerbations of chronic rhinosinusitis over time.METHODS:
Retrospective review of patients with recurrent acute exacerbations of chronic rhinosinusitis who underwent endoscopic-guided cultures during acute exacerbations of chronic rhinosinusitis.RESULTS:
386 cultures were obtained from 112 patients during recurrent acute exacerbations of CRS. A change of bacterial isolates during the course of recurrent exacerbations was observed in 68% (76/112) of patients, necessitating a change of treatment in 40% (45/112). The main risk factor for the subsequent change in cultures was polymicrobial growth. Sinus surgery was not associated with subsequent change in cultured isolates. Resistant strains developed in 11.6% (13/112) of patients, of whom those with abnormal mucociliary clearance being at the highest risk.CONCLUSION:
Repeated middle meatal cultures should be considered in patients with recurrent exacerbations of CRS, particularly in cases not responding to standard therapy.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Sinusitis
/
Bacteriología
/
Rinitis
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Eur Arch Otorhinolaryngol
Asunto de la revista:
OTORRINOLARINGOLOGIA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Israel