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Green asymmetric synthesis of epoxypeptidomimetics and evaluation as human cathepsin K inhibitors.
Silva, Taynara L; Dos Santos, Deborah A; de Jesus, Hugo C R; Brömme, Dieter; Fernandes, João B; Paixão, Marcio W; Corrêa, Arlene G; Vieira, Paulo C.
Afiliación
  • Silva TL; Department of Chemistry, Federal University of São Carlos, 13565-905 São Carlos, SP, Brazil; Faculty of Dentistry and UBC Center for Blood Research, 2350 Health Sciences Mall, Vancouver, BC V6T1Z3 Canada.
  • Dos Santos DA; Centre of Excellence for Research on Sustainable Chemistry, Department of Chemistry, Federal University of São Carlos, 13565-905 São Carlos, SP, Brazil.
  • de Jesus HCR; Department of Chemistry, Federal University of São Carlos, 13565-905 São Carlos, SP, Brazil.
  • Brömme D; Faculty of Dentistry and UBC Center for Blood Research, 2350 Health Sciences Mall, Vancouver, BC V6T1Z3 Canada.
  • Fernandes JB; Department of Chemistry, Federal University of São Carlos, 13565-905 São Carlos, SP, Brazil.
  • Paixão MW; Centre of Excellence for Research on Sustainable Chemistry, Department of Chemistry, Federal University of São Carlos, 13565-905 São Carlos, SP, Brazil.
  • Corrêa AG; Centre of Excellence for Research on Sustainable Chemistry, Department of Chemistry, Federal University of São Carlos, 13565-905 São Carlos, SP, Brazil. Electronic address: agcorrea@ufscar.br.
  • Vieira PC; Centre of Excellence for Research on Sustainable Chemistry, Department of Chemistry, Federal University of São Carlos, 13565-905 São Carlos, SP, Brazil; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, 14040-903 Ribeirão Preto, SP, Brazil. Electronic address: pcvieira@fc
Bioorg Med Chem ; 28(15): 115597, 2020 08 01.
Article en En | MEDLINE | ID: mdl-32631567
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inhibidores de Cisteína Proteinasa / Compuestos Epoxi / Catepsina K / Peptidomiméticos Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inhibidores de Cisteína Proteinasa / Compuestos Epoxi / Catepsina K / Peptidomiméticos Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article